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RWD Motorized Micromanipulator Redefines Precision to Highly Improve Microinjection Success Rate

RWD Motorized Micromanipulator Redefines Precision to Highly Improve Microinjection Success Rate

RWD Motorized Micromanipulator Redefines Precision to Highly Improve Microinjection Success Rate

Product catalog summary
Introduction: The document introduces the Motorized Micromanipulator MM-500, a device designed to enhance precision in microinjection processes. It highlights the device's capability to achieve movements as small as 33 nanometers, which is a significant improvement in precision.
Specifications: The MM-500 utilizes a two-phase hybrid stepping motor that allows for nanometer-level movement accuracy. This motor converts electrical impulses into mechanical motion, enabling precise control over movement, speed, and rotation angle.
Integration with Other Devices: The MM-500 can be combined with the R-480 Nanoliter Injection Pump and the MP-500 Micropipette Puller to perform ultra-fine microinjections. This combination is particularly useful for injecting substances into small biological samples such as eyeballs, zebrafish, nematodes, and other embryos and larvae.
Applications: The document outlines several applications for the MM-500, including:
  • Eyeball injection: Allows for steady and quantitative movement of the injection needle.
  • Intracranial virus or tracer injection: Facilitates stable needle movement for brain-directed injections.
  • Microinjection of zebrafish embryos: Enables DNA injection into embryos through precise movement of a glass microelectrode.
  • Insect and protozoan egg cells, larvae injection: Suitable for species like Drosophila and C. Elegans.
  • Other studies requiring precise needle movement at any angle.
Conclusion: The MM-500 micromanipulator significantly improves the precision and success rate of microinjections, making it a valuable tool in various biological and medical research applications.
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Catalog excerpts

RWD Motorized Micromanipulator Redefines Precision to Highly Improve Microinjection Success Rate-1

Motorized Micromanipulator Redefines Precision to Highly Improve Microinjection Success Rate Can you handle the movement tiny to 33nm? Motorized Micromanipulator MM-500 manage it for you. The diameter of ordinary hair is generally between 0.06 and 0.09 mm, 1mm= 1000μm, 1μm= 1000nm. Just turn the button, 33nm-the highest accuracy in three dimensions, which is hardly imagined to be realized in your finger. How to precisely achieve 33nm movement? It relies on a stepper motor, an electromechanical device that directly converts electrical impulses into mechanical motion. The MM-500 micromanipulator can control the steering, speed and rotation angle of the stepping motor by adjusting the sequence, frequency and quantity of electrical pulses applied to the motor coil. The following picture vividly demonstrates how a stepper motor works. -1-

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RWD Motorized Micromanipulator Redefines Precision to Highly Improve Microinjection Success Rate-2

MM-500 micromanipulator use a two-phase hybrid stepping motor with software operation, which can achieve nanometer-level movement accuracy and carry larger loads. So stepper motors are essential to achieve fine movements. What’s more, combine with R-480 Nanoliter Injection Pump and MP-500 Micropipette Puller, (https://www.rwdstco.com/product-item/r480-nanoliter-injection-pump/) (https://www.rwdstco.com/product-item/mp-500-micropipette-puller/) it can complete ultra-fine microinjection of eyeballs, zebrafish, nematodes and other embryos and larvae. For example the following picture: Even 0.6nl...

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RWD Motorized Micromanipulator Redefines Precision to Highly Improve Microinjection Success Rate-3

Applications: Eyeball injection: MM-500 can move the injection needle at any angle steadily and quantitatively at a constant speed. Intracranial virus or tracer injection: MM-500 meets the stable movement of the injection needle at any angle. Such as, brain-directed injection of AAV1/GFP vectors into hippocampus. Microinjection of zebrafish embryos: The DNA is injected into the embryo by moving the glass microelectrode through the chorion and blastomere. Insect and protozoan egg cells, larvae injection (e.g. Drosophila, C. Elegans) Other studies that require the needle to be held at any angle...

 Open the catalog to page 3

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