ambr® 250 modular - 12 Pages

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ambr®  250 modular

Catalog excerpts

sartoriusstedim biotech ambr® 250 modular Single-Use Benchtop Bioreactor with Simplified Operation for Increased Productivity turning science

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New Advanced Benchtop Bioreactor System for Parallel Microbial and Cell Culture ambr® 250 modular is an innovative new high performance benchtop bioreactor system for parallel microbial or cell culture in 100 - 250 mL single-use vessels. The system utilizes the same advanced stirred tank bioreactor technology pioneered in the original ambr® 250 high throughput system. The system comprizes a series of elegantly designed benchtop modules enabling 1 to 8 bioreactors to be operated in parallel and a control module with intuitive system software accessed via a user-interface screen. ►...

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ambr® 250 modular System Combines 1 to 8 Bioreactor Stations and a Control Module with System Software The modular design is expandable up to 8 bioreactors. Bioreactor module Holds 2 bioreactor stations. Up to 4 modules can be connected to the controller. Fast-loading peristaltic pump Accessible for each bioreactor, provides an alternative route for feeding and harvesting. This is in addition to the 5 integrated syringe pumps in each bioreactor.

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Chilled liquid reservoir Chills liquids to temperatures between 6-8°C ensuring temperature sensitive media can be maintained. 3 step 'Easy Connect' installation for all gas, liquid and sensor connections - Step 1 - slot in - Step 2 - secure with clamp - Step 3 - secure pH connector Enabling quick set-up and rapid turnaround. Touch screen user-interface Enabling easy control and supervision of multiple bioreactors. Bioreactor controller Manages all processes including pH, temperature and DO for up to 8 bioreactors. Fully integrated foam control. Optional off-gas analyzer Monitors and...

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Each bioreactor is fully integrated with 5 liquid reservoirs and proprietary single-use syringe pumps. The integration    Visible liquid addition lines simplifies experimental set-up, eliminates any need for    Allow view of liquid dirnng vessel sterilization, and significantly reduces any error    auto-priming. Vessel scalability Vessels are geometrically similar to standard bench and pilot scale bioreactors, enabling straightforward scale-up. Single-use mammalian or microbial bioreactors - 100 - 250 mL working volume. - Dual pitch blade or Rushton impellers. - Spot based DO sensor. -...

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Fully integrated liquid lines and reservoirs Allowing for rapid experimental set-up and turnaround. Gas tube Gases can either be delivered into the headspace or sparged into the media. These delivery systems are independent and can function in parallel. Septum cap Allows for rapid liquid additions with a syringe. Single-use pH and DO sensors Both pre-calibrated, the DO spot measures 0 - 200% and the standard pH probe has a measurement range of 2 - 8.5. Double impeller - Rushton or pitch-blade For microbial or mammalian vessels respectively. 7

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Software ambr® 250 modular is supplied with the same advanced software as the established ambr 250 high throughput system. Users can design new and complex experiments and analyze results easily and quickly. ambr 250 modular software encompasses 4 applications all of which enable export and import of data to | from different sources. Experiment Viewer Historian application which enables users to fully analyze experiments looking at audit trails, all variables and completed recipes. Process Definition Simple ‘drag and drop’ process steps for quick and easy definition of experiments. Runtime...

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- Individual bioreactor temperature control with heating and cooling. - Individual impeller speed control per bioreactor. - Optional off-gas analysis by BioPAT ambr Xgas for CO2 and O2, also uses OUR and CER measurements. Functions ambr® 250 modular automatically controls and adds liquids to 1 to 8 bioreactor | fermenter vessels in parallel Bioreactor controller - Three gasses per bioreactor with mass flow sensor: - Mammalian - O2 - CO2 - N2 | air - Microbial - O2 - Air - N2 - Five positive displacement liquid pumps per bioreactor for high precision at low flow rates. Applications ambr® 250...

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Single-Use from Cell Line and Process Development to Production Scale - Geometrical similarity of vessel design - Consistent mixing and gassing strategies - Reliable single-use platform

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BIOSTAT® B UniVessel® Glass 0.5 – 10 L working volume Biostatl® Cplus 5 - 30 L working volume Also scalable to glass and stainless steel bioreactors scaling up from 0.25 L to 1000 L Producti

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For further contacts, visit www.sartorius-stedim.com Europe America Germany Sartorius Stedim Biotech GmbH August-Spindler-Strasse 11 37079 Goettingen Phone +49.551.308.0 Fax +49.551.308.3289 Sartorius Stedim Systems GmbH Robert-Bosch-Strasse 5 - 7 34302 Guxhagen Phone +49.5665.407.0 Fax +49.5665.407.2200 France Sartorius Stedim FMT S.A.S. ZI des Paluds Avenue de Jouques - CS 91051 13781 Aubagne Cedex Phone +33.442.845600 Fax +33.442.845619 Sartorius Stedim France SAS ZI des Paluds Avenue de Jouques - CS 71058 13781 Aubagne Cedex Phone +33.442.845600 Fax +33.442.846545 Austria Sartorius...

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