Catalogs >
Sartorius Group >
How to Set Up a Pipetting Quality Control Program for Your Lab

How to Set Up a Pipetting Quality Control Program for Your Lab
4Pages

Catalog excerpts

How to Set Up a Pipetting Quality Control Program for Your Lab - 1

Application Guide September 2018 Keywords or phrases: Pipette Calibration, Pipette Maintenance, Pipette Service, Pipette Control How to Set Up a Pipetting Quality Control Program for Your Lab Improve the Quality of Pipetting and Reliability of Results Abstract Calibration, maintenance, and regular control of tools are essential to ensure the highest quality standards of laboratory work. For pipettes, the best practice would be to do calibration and maintenance according to the manufacturer’s recommendations at least annually or biannually, as well as implement a program for regular testing of pipette performance during use and between calibration intervals. This practical guide outlines the requirements for in-lab testing program, as well as for professional calibration and maintenance services. Find out more: www.sartorius.com

Open the catalog to page 1

How to Set Up a Pipetting Quality Control Program for Your Lab - 2

In-Lab Testing Routine Many quality systems and standards, such as Good Laboratory Practice (GLP), Good Manufacturing Practice (GMP), and the ISO 9000 series require that a regular, documented maintenance and calibration procedure must be in place for all instruments. Some labs, especially accredited laboratories, also require regular calibration of pipettes in ISO 17025 certified accredited calibration facility due to the security and traceability of results it brings. The good quality program of pipettes is a combination of regular day-to-day in-house checks and regular professional...

Open the catalog to page 2

How to Set Up a Pipetting Quality Control Program for Your Lab - 3

Calibration and Maintenance Program Most laboratory quality systems require a regular calibration and maintenance program for pipettes. Today, laboratories commonly use an external service provider for this laborintensive work that requires highly sophisticated quality systems. 1. What Should Be Done? The pipettes should be maintained according to the manufacturer’s instructions regularly. The maintenance consists of the cleaning and greasing of pipettes, as well as replacement of wearable parts. Alongside maintenance, the pipettes should have their performance verified by...

Open the catalog to page 3

How to Set Up a Pipetting Quality Control Program for Your Lab - 4

Best Practices for Setting up the Pipetting Quality Control Program To work according to Good Laboratory Practice, a Standard Operating Procedure (SOP) for Pipette Quality Control should be defined. Below are areas that should be described at minimum in the SOP to guide laboratory personnel through the process: 1. For in-lab testing routine, define: a. Testing frequency b. Testing equipment and environment c. Personnel qualifications to conduct testing d. Measured volumes and aliquot quantities e. Acceptance criteria f. How to record and store the results g. Actions of isolating and marking...

Open the catalog to page 4