Octet® R2 System
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Product Datasheet The System that Grows with Your Biomolecule Characterization Needs Key Features and Benefits Most budget-friendly option designed for academic and start-up labs Flexibility of field upgrade to a 4-channel or 8-channel Octet® system for higher throughput High-quality kinetic screening and affinity characterization Microfluidics-free Dip and Read format reduces assay time and maintenance cost Crude sample compatibility saves valuable time by eliminating the need for sample pre-treatment Two parallel, independent channels, with the flexibility of using the second channel for a reference or for more samples Versatility to detect and analyze a diverse range of biomolecules from small molecules to viruses Non-destructive sampling to conserve precious samples for other assays Equipped with sample plate cooling for temperaturesensitive proteins and assays Easy to learn and use Integrated acquisition and analysis software eliminates dependency on external software.

Product Information The 2-channel Octet® R2 system offers an advanced, fluidics-free approach to protein analysis, with a wide variety of off-the shelf Dip and Read biosensors for rapid binding kinetics and quantitation analysis. This system utilizes Sartorius’ label-free Bio-Layer Interferometry (BLI) technology, enabling direct detection of specific proteins and other biomolecules — even in complex mixtures like crude cell culture supernatants and lysates. Priced for academic and start-up customers, The Octet® R2 system offers low-cost access to accurate and sensitive biomolecular...

The Octet® R2 system monitors binding events in real time to calculate on rates (ka), off rates (kd) and affinity constants (KD). The superior sensitivity of the system enables measurement of small (Figure 2) and large (Figure 3) molecules and kinetic constants over a broad range. The sample plate temperature can be controlled from 15–40°C, which enables reliable kinetic determinations at different temperatures for temperature-sensitive proteins. Additional advantages of sample cooling include the ability to rapidly determine binding rate constants at multiple temperatures to extrapolate...

Octet® BLI Discovery and Analysis Studio Software Pre-defined templates in Octet® BLI Discovery Software streamlines setup prior to running an assay and minimizes training needs. Octet® Analysis Studio Software can overlay data from multiple plates over an extensive range of parameters and metrics to analyze acquired data from an entire project, thereby reducing analysis time from hours to minutes. All settings in Octet® Analysis Studio Software can be saved and re-loaded for new similar datasets to speed up routine assays. The software can also generate customized reports of the...

Octet® R2 System Technical Specifications1 Technical information and specifications Detection technology Biosensor type Disposable, single-use fiber optic biosensors with optional reuse by regeneration and/or re-racking in the biosensor tray Information provided Data presentation Sample types Yes/No binding Kinetic and affinity analysis (kobs, ka, kd, KD) Specific and selective detection of molecules, even in crude samples Relative and absolute quantitation of specific proteins in crude matrices or purified samples Graphs displaying real-time kinetic binding traces, fitted result plots and...

Ordering Information Part No. Includes Octet® R2 instrument, Octet® Software, desktop computer, LCD monitor, accessory kit and one-year warranty Octet® R2 Installation and Operational Qualification Kit Related Products Part No. Includes Octet® R4 instrument, Octet® Software, desktop computer, LCD monitor, accessory kit and one-year warranty Octet® R4 Installation and operational qualification kit Includes Octet® R8 instrument, Octet® Software, desktop computer, LCD monitor, accessory kit and one-year warranty Includes Octet® R8 instrument, Octet® 21 CFR Part 11 Software, desktop computer,...

Germany Sartorius Lab Instruments GmbH & Co. KG Otto-Brenner-Strasse 20 37079 Goettingen Phone +49 551 308 0 USA Sartorius Corporation 565 Johnson Avenue Bohemia, NY 11716 Phone +1 888 OCTET 75 Or +1 650 322 1360 Find out more: www.sartorius.com/octet-support For questions, email: AskAScientist@sartorius.com Specifications subject to change without notice. © 2021. All rights reserved. Octet® and all names of Sartorius products are registered trademarks and the property of Sartorius AG and/or one of its affiliated companies. Octet-R2-System-Datasheet-FB-4039-B-en-L-Sartorius Status: 09 | 2021