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Unisart® CN 180 DX Membrane

Unisart® CN 180 DX Membrane
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Product Information Introduction The Unisart® CN 180 DX membrane is the newest lateral flow membrane in our portfolio. It combines high protein binding capacity with superior sensitivity for critical applications such as HIV and malaria tests. All raw materials are REACH compliant. Unisart® CN 140 is the gold standard in our portfolio. This membrane is suitable for a broad range of applications, as it offers a good balance between protein binding, sensitivity, and capillary speed. For critical applications, such as infectious diseases (e.g., HIV and malaria), very high protein binding and sensitivity is needed. Therefore, Unisart® CN 180 DX was developed. The new membrane has a nominal pore size of 5 µm, which is the smallest in our product portfolio. As a result, the inner surface area is increased, and more protein can be bound. The combination of increased protein binding and decreased capillary speed, results in enhanced signal intensity. In the following, we compare our gold standard Unisart® CN 140 with the new Unisart® CN 180 DX in terms of protein binding capacity and sensitiv

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Protein Binding Capacity Protein Binding Capacity (%) The new Unisart® CN 180 DX shows high protein binding capacity, as demonstrated in Figure 1. The protein binding capacity for Unisart® CN 180 DX is 30 % higher than for Unisart® CN 140. Figure 1. Comparison of protein binding capacity: To identify the protein binding capacity of Unisart® CN 140 and CN 180 DX, a BCA test was performed of five different lots for each Unisart® CN membrane type. The average protein binding capacity was normalized and is depicted as bar diagram in percentage. The protein binding capacity of Unisart® CN 180 DX...

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We performed a flu A test as an example for an infectious disease assay (Figure 3). The flu A test confirms the high binding capacity and signal intensity of Unisart® CN 180 DX. As shown in Figure 3, the signal intensity is about 25 % higher than for Unisart® CN 140. Test Line Intensity (%) Test Performance Figure 3. Comparison of test performance: To show the performance of Unisart® CN 140 and Unisart® CN 180 DX, the membranes were used in a flu A test. For this, anti-flu A antibody was printed on the test line (1 mg/mL) and conjugated to latex beads (400 nm). Recombinant flu A...

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Germany Sartorius Lab Instruments GmbH & Co. KG Otto-Brenner-Strasse 20 37079 Goettingen Phone +49 551 308 0 For further contacts, visit Specifications subject to change without notice. Copyright Sartorius Lab Instruments GmbH & Co. KG. Publication No.: Unisart-CN-180DX- Product-Information-en-L-Sartorius Version: 11 | 2022

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Unisart® CN 180 DX Membrane
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