Analytical solution for high-throughput drug discovery assays Selecting the right analytical technology to support drug discovery is a key decisionThis infographic compares different analytical technology in this space AEMS at a glance > 2.5 nL Fast method development time Low consumable Sample volume usedrequirements Fast sample preparation time Up to 1 sample per Data acquisition time [30 min 1536 well plate] Data quality you can rely on [Low false positive/negative rate] Desirability score: AEMS SPE-MS Plate Reader Acoustic ejection mass spectrometry Solid phase extraction - mass spectrometry Instrument purchase price Instrument size Method development time •#o #oo Consumable requirements and cost Sample volume Sample preparation time •#o #oo Data acquisition time 10 mins [384 well plate] Approx, 8 sec per sample with SPE 21- 38 sec per plate 30 min [1536 well plate] [S to 153S wells per plate] False positive/negative rate •#o #oo Don't compromise Obtain high quality data at speed Plate readers are well established for high throughput screening assays because they are cost-effective and have a favorable throughput for common assays. However, they reguire significant skill and method development time to select the optimum labelling-reagent, and the reagents themselves can be expensive. AEMS is more expensive to purchase but benefits from the specificity of mass spectrometric detection and the ability to measure a more diverse range of compounds. Being a label-free technigue reduces the method development time and confidence in the accuracy of the results. Learn more
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