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Brochure: AB SCIEX SelexION Technology: A New Dimension in Selectivity

Brochure: AB SCIEX SelexION Technology: A New Dimension in Selectivity

Brochure: AB SCIEX SelexION Technology: A New Dimension in Selectivity

Product catalog summary
Introduction to SelexION™ Technology
AB SCIEX SelexION™ Technology is an advanced ion mobility separation tool designed to enhance data quality in the quantitation and characterization of complex samples. It offers improved selectivity and performance, particularly for applications requiring the separation of isobaric species and reduction of background noise.
Key Features and Benefits
  • Enhanced Selectivity: SelexION™ technology provides a new dimension of selectivity for the AB SCIEX Triple Quad™ 5500 and QTRAP® 5500 Systems, improving the separation of challenging co-eluting contaminants.
  • Transformational Analytical Power: The technology enhances analytical selectivity and data quality, making the systems the most sensitive and selective in their class.
  • Cost-Effective Efficiency: The technology is easy to install, requiring less than two minutes, and can be operated on-demand without removing hardware.
Technical Specifications
  • SelexION Differential Ion Mobility Cell: A compact design that allows for tool-free installation.
  • Qurved LINAC® Collision Cell: Accelerates ions for faster analysis and eliminates cross-talk, ideal for high throughput analysis.
  • Linear Accelerator™ Trap: Improves extraction efficiency, offering up to a 100x gain in sensitivity in ion trap scan modes.
Applications and Performance
  • Bioanalysis: Meets standards for reproducibility and robustness, with improved signal-to-noise ratios and lower limits of quantitation (LLOQ).
  • Complex Sample Analysis: Reduces background interferences and enhances separation power using integrated chemical modifiers.
  • Reproducibility and Stability: Demonstrated through extensive testing with low coefficient of variation (CV) percentages in peak areas.
Support and Services
AB SCIEX provides extensive service and support, including a network of service professionals and application scientists. The company offers flexible service plans and comprehensive customer support to ensure optimal use of their systems.
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Catalog excerpts

Brochure: AB SCIEX SelexION Technology: A New Dimension in Selectivity-1

AB SCIEX SELEXION ™ TECHNOLOGY A new dimension in selectivity AB SCIEX SELEXION ™ TECHNOLOGY

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Brochure: AB SCIEX SelexION Technology: A New Dimension in Selectivity-2

Discover a new dimension of selectivity Advanced performance AB SCIEX SelexION™ Technology is an effective ion mobility separation tool for improving data quality in the quantitation and characterization of challenging samples requiring advanced analytical selectivity. Enhanced selectivity SelexION™ technology on the AB SCIEX Triple Quad™ 5500 and QTRAP® 5500 Systems delivers a new dimension of selectivity and performance for any application requiring the separation of isobaric species, isolation of challenging co-eluting contaminants and reduction of high background noise. Transformational analytical...

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Brochure: AB SCIEX SelexION Technology: A New Dimension in Selectivity-3

Reproducible, robust and easy to use SelexION™ technology supports highly selective quantitative and qualitative LC/MS/MS workflows with the AB SCIEX Triple Quad™ 5500 and QTRAP® 5500 Systems. Bring a new dimension of selectivity, simplicity and cost-effective efficiency to your LC/MS/MS analysis • Add differential ion mobility separation with a small, easily interchangeable unit • Increase peak separation power further through use of the Integrated Chemical Modifier mode Meet bioanalysis standards for reproducibility and robustness Match cycle and run times with multi-component analysis and...

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Brochure: AB SCIEX SelexION Technology: A New Dimension in Selectivity-4

SelexION technology–enhanced selectivity in an elegantly simple package ™ No other ion mobility separation tool has the reproducibility, robustness and ease of use to deliver highly selective and sensitive quantitative and qualitative analyses, within an UHPLC time scale and over multiple MRMs simultaneously – all on the worlds most sensitive triple quadrupole and QTRAP® platforms. SelexION Differential Ion Mobility Cell Compact and simple design allows the cell to be installed without the use of any tools and in less than 2 minutes. SelexION Curtain Plate Updated version of the traditional curtain...

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Brochure: AB SCIEX SelexION Technology: A New Dimension in Selectivity-5

Patented Linear Accelerator™ Trap Bringing LINAC® technology to the Q3 linear ion trap greatly improves the extraction efficiency to yield up to a 100 x gain in sensitivity in ion trap scan modes. Now take full advantage of the 20,000 Da/s scan speeds without worrying if enough sensitivity is on board to generate incomparable results. Improved excitation efficiencies and reduced ion cooling and fragmentation times produce superior MS3 qualitative results and provide unprecedented selectivity for the most challenging analytical assays. Patented Qurved LINAC® Collision Cell The newly designed Qurved...

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Brochure: AB SCIEX SelexION Technology: A New Dimension in Selectivity-6

New dimensions of selectivity and sensitivity One simple package for isobaric species, co-eluting contaminants, and signal-to-noise improvements. Challenged by assays with isobaric interferences and difficult to separate co-eluting contaminants? SelexION™ technology offers a fast, reproducible and easy-to-use solution that enhances the selectivity of your assays. • Conduct differential mobility separations of multiple MRMs, with a cycle time of 25 ms per MRM Enhance separation power with use of integrated chemical modifiers such as IPA Perform a gas phase differential ion mobility separation...

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Brochure: AB SCIEX SelexION Technology: A New Dimension in Selectivity-7

Peak area Buprenorphine, CV% = 6.8% Peak area Clenbuterol, CV% = 5.6% IS corrected Peak area Buprenorphine, CV% = 1.7% IS corrected Peak area Clenbuterol, CV% = 1.6% The above figure of 1000 injections of spiked Buprenorphine and Clenbuterol in protein precipitated human plasma demonstrates the unique reproducibility, robustness and stability of the SelexION™ technology in combination with the AB SCIEX QTRAP ® 5500 System. A total of 66 hours of consecutive analysis produced a % CV of less than 7% in the peak area for both Buprenorphine and Clenbuterol. Multiplied selectivity Significantly reduce...

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Brochure: AB SCIEX SelexION Technology: A New Dimension in Selectivity-8

You invest in our technology. We invest in your success. As the world leader in mass spectrometry, AB SCIEX solutions are backed by the industry’s most extensive service and support organization. With a network of service professionals, experienced compliance specialists, and over 150 PhD application scientists worldwide, we are dedicated to supporting your technical needs and helping you get the most out of your AB SCIEX systems. AB SCIEX service professionals are recognized as the most highly qualified in the industry. They are certified on our instrument platforms through a rigorous 4-step...

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Archived catalogs

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