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LC/MS/MS Solutions For Clinical Research

LC/MS/MS Solutions For Clinical Research

LC/MS/MS Solutions For Clinical Research

Product catalog summary
Introduction
LC/MS/MS (Liquid Chromatography with Tandem Mass Spectrometry) is increasingly adopted in clinical research for its ability to perform trace level quantitation of multiple compounds. AB SCIEX provides solutions that facilitate the integration of LC/MS/MS technology into clinical research laboratories, offering benefits such as faster return on investment, superior sensitivity, and reduced sample preparation time.
Specifications and Features
AB SCIEX's LC/MS/MS solutions are designed for ease of use, even for those without prior mass spectrometry experience. The technology offers high specificity and low detection limits, ensuring accurate results. The systems are robust, ensuring maximum uptime and supported by global service networks.
Applications in Endocrinology and Biomarker Research
LC/MS/MS is ideal for analyzing complex matrices like blood and urine, identifying panels of steroids, vitamin D metabolites, and proteins. It allows for the simultaneous analysis of multiple compounds, increasing throughput and minimizing sample consumption. Pre-configured methods are available for various analytes, including testosterone, estrogens, and vitamin D.
Inborn Errors of Metabolism and Amino Acid Studies
AB SCIEX provides methods for analyzing inborn errors of metabolism, allowing simultaneous analysis of amino acids and acylcarnitines. The solutions offer faster analysis times compared to conventional methods, with run times of less than 18 minutes per sample.
Therapeutic Drug Monitoring
LC/MS/MS is used for therapeutic drug monitoring, particularly for low-dose, multi-drug regimens. It provides accurate quantification of drugs like immunosuppressants and antiretrovirals, with methods that simplify sample preparation and reduce run times.
Toxicology Applications
LC/MS/MS is valuable for toxicology screening, offering simplified sample preparation and faster run times compared to GC/MS. It can detect and quantify drugs of abuse at lower levels, with the ability to analyze hundreds of drugs in a single run.
Software and Support
AB SCIEX offers powerful software solutions like Cliquid® and ChemoView™ for simplified analysis and data management. The company provides comprehensive training, service, and support to ensure efficient use of their systems.
Conclusion
AB SCIEX is committed to supporting clinical research laboratories with advanced LC/MS/MS solutions, backed by extensive service and support. Their technology enables researchers to achieve faster, more accurate results, enhancing the overall efficiency of clinical research operations.
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Catalog excerpts

LC/MS/MS Solutions For Clinical Research-1

LC/MS/MS SOLUTIONS FOR CLINICAL RESEARCH The highest level of confidence LC/MS/MS SOLUTIONS FOR CLINICAL RESEARCH

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LC/MS/MS Solutions For Clinical Research-2

For Research Use Only. Not for use in diagnostic procedures. The limitations of conventional analytical techniques are accelerating the adoption of mass spectrometry as a smart alternative for scores of clinical research applications that involve trace level quantitation of multiple compounds such as endocrine analytes, biomarkers, and drugs of abuse. AB SCIEX delivers easy-to-use solutions that speed the adoption of LC/MS/MS by clinical researchers. Combining best-in-class technologies, advanced software, and pre-configured analytical methods, AB SCIEX enables clinical research laboratories...

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LC/MS/MS Solutions For Clinical Research-3

LC/MS/MS solutions for endocrinology and biomarker research LC/MS/MS is ideally suited to identify panels of steroids, vitamin D and its metabolites, peptides or proteins, and other compounds in complex matrices such as blood, urine, saliva and whole cell lysates. Tandem mass spectrometry is becoming an essential tool for research applications in endocrine and biomarker analysis. Unlike conventional immunoassay methods, LC/MS/MS enables highly selective and specific analysis of multiple compounds in a single • Multi-analyte steroid panel • T3/T4 and FT3/FT4 • Homocysteine run, leading to more...

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LC/MS/MS Solutions For Clinical Research-4

LC/MS/MS solutions for inborn errors of metabolism and amino acid studies Inborn Errors of Metabolism Amino Acid Analysis Move your research ahead Faster time to result AB SCIEX solutions enable you to use LC/MS/MS for classical The AB SCIEX solution for LC/MS/MS analysis of amino acids neonatal screening research and expand into other applications is faster than conventional research methods and uses labeled related to inborn errors of metabolism such as research into internal standards for more accurate and robust quantitation, lysosomal storage disorder, bile acids, very long chain fatty acids...

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LC/MS/MS Solutions For Clinical Research-5

LC/MS/MS solutions for research into therapeutic drug monitoring The development of new therapeutic drug monitoring (TDM) methods is an area of intense research due to: • The need for low-dose, multi-drug regimens • The importance of assessing inter- and intra-individual metabolism variability • The necessity of determining the narrow therapeutic concentration ranges As a result, clinical research laboratories are turning to LC/MS/MS to analyze immunosuppressant, antiretroviral, anticonvulsive, and antipsychotic drugs. Get it done AB SCIEX LC/MS/MS solutions quickly identify and quantify low-dose,...

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LC/MS/MS Solutions For Clinical Research-6

LC/MS/MS solutions for toxicology LC/MS/MS has become a very valuable tool for toxicology screening in clinical research. Compared to other techniques such as GC/MS, by using LC/MS/MS, sample preparation can be simplified and run times reduced, resulting in increased throughput and faster sample turnaround times. In addition, the sensitivity of LC/MS/MS quantitative methods is capable of detecting and quantifying drugs of abuse at significantly lower levels than GC/MS. Identify and quantify hundreds of drugs in a single analysis Unique AB SCIEX QTRAP® System technology enables shortened analysis...

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LC/MS/MS Solutions For Clinical Research-7

Proven solutions for confident results AB SCIEX provides a variety of tools to simplify implementation of LC/MS/MS. Our state-of-the-art hardware provides unparalleled sensitivity for high-quality results and rugged instrumentation for maximum uptime. Cliquid® Software combined with iMethod™ Applications can get your clinical research laboratory running commonly requested assays quickly and effortlessly. Whether you are seeking an ultrasensitive assay for quantification of a single analyte or a high-throughput, multi-component method, AB SCIEX can customize a solution to meet your needs. High...

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LC/MS/MS Solutions For Clinical Research-8

You invest in our technology. We invest in your success. As the world leader in mass spectrometry, AB SCIEX creates solutions that are backed by the industry’s most extensive service and support organization. With a network of service professionals, experienced compliance specialists, and over 150 PhD application scientists worldwide, we are dedicated to supporting your technical needs and helping you get the most out of your AB SCIEX systems. AB SCIEX service professionals are recognized as the most highly qualified in the industry. They are certified on our instrument platforms through a rigorous...

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