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STAT-NAT® HHV-6

Product catalog summary

Overview: The document describes the STAT-NAT® HHV-6 Lyophilized Real-Time PCR mix, a diagnostic kit for detecting and quantifying Human Herpesvirus 6 (HHV-6) in human samples. The kit is designed for use in molecular biology techniques and offers several advantages including room temperature storage and ease of use.

Specifications: The kit is available in a size of 48 tests and is validated on CFX96 (Bio-Rad) and QS5 (ABI) platforms. It includes all necessary reaction components, including the Hot Start Polymerase enzyme.

Key Features:

Flexibility: Enhances test sensitivity even with low DNA concentrations.
Universal Application: Performs well across various molecular biology techniques.
Environmental Sustainability: Requires no cumbersome packaging or temperature-controlled shipping.
Storage: Freeze-dried for long-term room temperature storage.
Ease of Use: Ready-to-use, minimizing analytical variables.

HHV-6 Information: HHV-6 is a Betaherpesvirinae subfamily virus with two subtypes, A and B. HHV-6B infects nearly all humans by age three, while HHV-6A can accelerate HIV progression. The virus can establish latency and reactivate, particularly in immunocompromised individuals, affecting various organs.

Kit Benefits:

Accurate quantification of HHV-6A and HHV-6B.
Useful for monitoring transplant patients.
Compatible with multiple human sample types.
Includes internal control and calibrators.

Performance Metrics:

Specificity: ≥95%
Analytical Sensitivity (LoD): 5 copies/reaction

Graphical Data: The document includes amplification and standard curve graphs demonstrating the kit's performance, with a high correlation coefficient (R²=0.998) and efficiency (E=106.4%).

Catalog excerpts

HHV-6 Lyophilized Real-Time PCR mix for the detection and quantification of HHV-6

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Available from June 2019 Molecular Biology made easy! HHV-6 Lyophilized Real-Time PCR mix for the detection and quantification of HHV-6 Human Herpesvirus 6 (HHV-6) is a member of the Betaherpesvirinae subfamily of human herpes viruses. There are two subtypes of HHV-6, type A and type B. HHV-6B infects nearly 100% of human beings, typically before the age of three. HHV-6A can promote the progression of HIV disease toward AIDS, as both clinical and experimental evidence suggest. Like other herpesviruses, HHV-6 establishes life-long latency and can become reactivated later in life. Reactivation...

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