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UIBC Liquid

Product catalog summary

Introduction
This document outlines the new formulation of UIBC Liquid, a diagnostic reagent used to measure unsaturated iron-binding capacity in serum samples. The product is developed by Sentinel CH. SpA, based in Milan, Italy.

Principle
The UIBC Liquid test involves adding a serum sample to an alkaline buffer/reductant solution with a known iron concentration. This saturates the iron-binding sites on transferrin. The unbound iron is reduced to a ferrous state and complexed with Ferene-S, forming a stable complex. The color intensity of this complex is measured at 580 to 600 nm, and UIBC is calculated by subtracting the unbound iron from the total iron added.

Features and Advantages

Liquid and ready-to-use formulation.
Linearity up to 500 µg/dL.
Sensitivity of 20 µg/dL.
Reagent onboard stability of 10 days.
Excellent correlation with other market methods.
Universal vials compatible with various analyzer series.
Standard material included in the kit.
Calibration onboard stability of 12 days.

Method Comparison
The document includes a method comparison between UIBC Liquid REF 17639 and UIBC Liquid REF 2P79-21, showing a linear fit with the equation (-8.90 + 1.09x). This comparison demonstrates the consistency and reliability of the new formulation across different validation lots and equipment.

Catalog excerpts

UIBC Liquid Unsaturated Iron-Binding Capacity NEW FORMULATION: TWO LIQUID REAGENTS

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UIBC Liquid Two Liquid Reagents Features and Advantages The serum sample is added to an alkaline buffer/ reductant solution containing a known concentration of iron to saturate the available iron-binding sites on transferrin. Linearity up to 500 µg/dL Sensitivity: 20 µg/dL Reagent onboard stability: 10 days Excellent correlation with other similar methods available on the market Reagents filled in Universal Vials suitable for AU series, ADVIA series, Roche Modular, Hitachi 917, DIRUI series, Mindray BS-800 Standard material included in the kit The remaining unbound iron after transferrin saturation...

Open the catalog to page 2

UIBC Liquid

UIBC Liquid

Catalog excerpts

All SENTINEL DIAGNOSTICS catalogs and technical brochures