Company Profile

Shanghai TOW Intelligent Technology Co., Ltd., established in 2018 and located in Songjiang District, Shanghai, specializes in the development and manufacturing of equipment for preclinical animal experiments. Their product range includes animal respiratory systems, inhalation exposure systems, hyperbaric and hypobaric chambers, tri-gas incubators for cell research, and metabolic science experimental equipment. The company integrates advanced technologies from life sciences, medicine, IT, electronics, and machinery to provide customized solutions.

Shanghai TOW Intelligent Technology emphasizes craftsmanship, integrity, and innovation to deliver reliable products for scientific research.

Product Features

• Easy to use with no operation required.
• Multi-channel simultaneous monitoring capability.
• Suitable for studying animal respiration in natural states and for long-term follow-up experiments, ideal for initial drug screening.
• Optional aerosol nebulization module available.
• Can monitor up to 16 mice or rats simultaneously.
• Optional drinking water and food ports for continuous long-term monitoring.
• Additional optional functions include ECG, blood pressure, body temperature, heart rate, and other vital signs measurements, compatible with implantable telemetry equipment.
• Equipped with analysis software allowing data export in Excel or TXT formats.

Applications

• Research on respiratory diseases such as asthma, pulmonary fibrosis, lung injury, ARDS, and lung cancer.
• Safety pharmacology to assess drug effects on the respiratory system.
• Sleep apnea studies including hypopnea and obstructive apnea monitoring.
• Environmental toxicology to evaluate the impact of pollutants on animal respiration.
• Inhalation toxicology assessing toxic substances' effects on the respiratory system.
• High altitude medicine studying the influence of high altitude on respiratory function.

Test Parameters

The system measures various respiratory parameters critical for research, including:

• Minute Ventilation (Mv) in milliliters
• Inspiratory Time (Ti) in seconds
• Expiratory Time (Te) in seconds
• Accumulated Volume (AV) in milliliters
• Mid-tidal Expiratory Flow (EF50)
• End-inspiratory Pause (EIP) and End-expiratory Pause (EEP) using invasive methods
• Peak Inspiratory Flow (PIF) and Peak Expiratory Flow (PEF) in ml/s
• Volume balance between inspiratory and expiratory volumes (Volbal)
• Relax Time (TR)
• Enhanced Pause (PenH)
• Ratio of Time to Peak Expiratory Flow (Rpef)
• Flow rate measured in breaths per minute (F)

Configuration and Additional Notes

The document references configuration details and includes graphical or tabular data illustrating test parameters, emphasizing the system's capability for comprehensive respiratory monitoring in animal models.

Critical Information: The system supports multi-animal monitoring with optional modules for extended physiological measurements, making it suitable for diverse respiratory and toxicological research applications. Data management is facilitated through compatible software enabling easy export and analysis.