HippoScreen Neurotech Corp It's all about your brain. Address : 11492 2F., No. 578, Ruiguang Rd., Neihu Dist., Taipei City 114, Taiwan (R.O.C.) Email : [email protected] Website https://www.hipposcreen-nc.com

Introduction According to statistics from the World Health Organization, approximately 280 million people in the world have depression. Depression is a leading cause of disability and a significant contributor to the global disease burden; severe cases can even lead to suicide. There are many known effective treatments for depression. However, correct diagnosis is crucial. Research indicates that 70% of patients with depression seek medical attention primarily due to various somatic symptoms, such as chest tightness, palpitations, unexplained pain. Additionally, 10% of patients completely deny...

Product Purpose The Stress EEG Assessment (SEA) system developed by HippoScreen Neurotech includes an EEG amplifier for data collection and signal processing, a GUI for test process control, and an AI algorithm for data analysis. It records 90-second brainwave signals to analyze with AI algorithm, and generates an objective stress index score and intuitive data distribution maps in the assessment report. SEA system is a powerful AI helper in mental health screening and clinical practice.

•* System Architecture Generate Login system The EEG amplifier (EAmp) suppresses noise and amplifies the subject's brainwave signal, performs analog-to-digital conversion, and then transmits it to the computer. The GUI provides user-friendly operation for the detection process, while data analysis is done through AI algorithms deployed on the cloud. The assessment report generated is also stored in the cloud database. The administrator can login to the report website to access the assessment results.

•* Detection Process Wear EEG Cap Fill in basic information and PHQ-9 questionnaire Inject gel into electrode The detection process is quite simple and it only takes about 15-20 minutes, including the setup of the detection and the generation of the assessment report. First, the operator will help the subject to wear the EEG cap, and guide the subject to fill in basic information and PHQ-9 questionnaire to make a simple self-assessment. Then the operator will inject the conductive gel to reduce the impedance and ensure the received EEG signal quality. After the setup is completed, the subject...

Actual Scene Because brainwave detection is sensitive to interference, it is suggested to be done in a separate room. When capturing 90second brainwave signals, avoiding sudden loud noises or light flickering, otherwise, the analysis results may be affected.

Assessment Report The data distribution map on the right side of the evaluation report is obtained by using the brain wave data collected by the IRB research project in cooperation with three medical centers in Taiwan, plus the subject's brain wave data for feature extraction and analysis. Color depth can be mapped to the SEA index ranging from 1 to 10, representing the probability of suffering from depression. The green dot is the data point for the test subject. The closer the green dot is to the dark area, the higher the stress of the test subject.

As for the nine-grid table on the left, it is a two-dimensional comprehensive evaluation of self-assessed result (the PHQ-9 score) versus the physiological result (the SEA index from the brainwave analysis). Through the evaluation, it can help professionals to understand the mental state of the subjects more comprehensively and accurately. The SEA system has both medical and non-medical applications. Checkup Corporation Community

The EEG amplifier is cleared by both USA FDA and Taiwan FDA. The SEA software is approved software as medical device (SaMD) by Taiwan FDA.

Open Access by © Chien-Te Wu "M" ® Hao-Chuan Huang 0 © shiuan Huang 2>t ® © i-Ming Chen ^ S @ Shih-Cheng Liao 30 @ Chih-Ken Chen 5 6 Q, © Chemsn Lin 5 6 Q - © Shwu-Hua Lee 6<7 s, © Mu-Hong Chen 8-9 © Chia-Fen Tsai 8-9 © Chang-Hsin Weng 2 Q, © Li-Wei Ko 10 B, © Tzyy-Ping Jung 11 * Sand © Yi-Hung Liu 12 * 0 0 1 International Research Center for Neurointelligence (WPI-IRCN), The University of Tokyo Institutes for Advanced Study (UTIAS), The University of Tokyo, Tokyo 113-0033. Japan 2 Hipposcreen Neurotech Corp (HNC), Taipei 114, Taiwan 3 Division of Psychosomatic Medicine, Department of Psychiatry,...

appliedsciences Article Depression Detection Using Relative EEG Power Induced by Emotionally Positive Images and a Conformal Kernel Support Vector Machine Chien-Te Wu 1,2/+, Daniel G. Dillon 3,4,t , Hao-Chun Hsu 5, Shiuan Huang5, Elyssa Barrick 3 1 School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei 10617, Taiwan; [email protected]. tw 2 Department of Psychiatry, National Taiwan University Hospital, Taipei 10617, Taiwan 3 Center for Depression, Anxiety and Stress Research, McLean Hospital, Belmont, MA 02474, USA; [email protected] (D.G.D.); [email protected]...

Shih-Cheng Liao 1-t, Chien-Te Wu 1'2'1, Hao-Chuan Huang 3, Wei-Teng Cheng 4 and Yi-Hung Liu 3'5’* 1 Department of Psychiatry, National Taiwan University Hospital, Taipei 10051, Taiwan; [email protected] (S.-C.F..); [email protected],tw (C.-T.W.) 2 School of Occupational Therapy, College of Medicine, National Taiwan University, Taipei 10051, Taiwan 3 Graduate Institute of Mechatronics Engineering, National Taipei University of Technology, Taipei 10608, Taiwan; [email protected] 4 Department of Mechanical Engineering, Chung Yuan Christian University, Chungli 32023, Taiwan; [email protected]...