AXIMA Confidence

AXIMA Confidence

AXIMA Confidence

Product catalog summary
Introduction
The document introduces the AXIMA Confidence™, a MALDI-TOF MS system designed for high sensitivity and flexibility in mass spectrometry applications. It is suitable for both manual and automated analysis across various sample types.

System Specifications
The AXIMA Confidence™ features a 50Hz N2 laser for rapid, high-quality spectra. It supports both linear and reflectron modes, with the latter providing high resolution and mass accuracy. The system includes positive and negative ion modes and a patented beam blanker to enhance flexibility and prevent detector saturation.

Software Solutions
The system is equipped with intuitive software for data processing and reporting, including PolymerAnalysis™ and OligoAnalysis™ for polymer and oligonucleotide analysis, respectively. It also supports biomarker discovery and tissue imaging with automated acquisition methods.

Applications
The AXIMA Confidence™ is ideal for proteomics, LC MALDI, polymer analysis, and tissue imaging. It offers application-centric data processing packages, including Intellimarque™ for proteomics, which integrates peptide mass fingerprinting and MS/MS for protein identification.

System Support
Comprehensive support is available through web-based diagnostics and local service engineers. Training courses are offered to ensure optimal use of the system.

Performance and Flexibility
The system achieves excellent sensitivity and resolution through advanced ion optics and pulsed ion extraction. It supports various sample target formats, compatible with laboratory robots, and offers seamless MS/MS capabilities.

Data Analysis
Data-dependent workflows and batch searching enhance protein identification confidence. The system allows for reprocessing and resubmission of data for further analysis.

Conclusion
The AXIMA Confidence™ provides a robust and flexible solution for life science and analytical laboratories, offering high performance and comprehensive software tools for a wide range of applications.
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Catalog excerpts

AXIMA Confidence-1

AXIMA Confidence ™ Taking MALDI-TOF MS Beyond the Standard Powerful MALDI-TOF performance for reliable mass information and MS/MS derived structural detail. An affordable robust option for all laboratories requiring routine manual or automated analysis of a wide variety of sample classes. High sensitivity system using a variable repetition rate 50 Hz N2 laser and a variety of target formats to meet all sample throughput requirements. Mascot® is a registered trademark of Matrix Science Ltd., London, UK. AXIMA , AXIMA Confidence , LAUNCHPAD , INTELLIMARQUE™, MonoPULSE™, Low Mass Zoom (LMZ)™ and Optimass™ are trademarks of Kratos Analytical Ltd., Manchester, UK. ™ ™ ™ Xcise™, Accuspot™ and ChIP™ are trademarks of Shimadzu Corporation, Kyoto, Japan. www.shimadzu-biotech.net [email protected] E & OE Ref: MO305 Issue 1

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AXIMA Confidence-2

Data-dependent MS/MS: using the results of the PMF search, MS/MS may be performed on ions that matched to the top ranked protein hit (confirmation MS/MS), in addition to those that were not (investigation MS/MS). ACTH fragment 7-38 showing >15,000 resolution FWHM % 100 90 80 70 Batch searching of these MS/MS spectra is then performed automatically to provide further and higher confidence protein identification. 60 50 40 30 20 10 0 55000 60000 65000 70000 m/z Bovine serum albumin in linear mode 75000 80000 1[c].G11 Data may be reprocessed and resubmitted for database searching at a later time...

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.