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Topics 2. Provides Improved Selectivity and Sensitivity via MRM Application Data Sheet With GC-MS/MS MRM mode, mass separation is performed in 2 stages, so background interferences from biological samples are easily separated from the target compounds, and the forensic toxicological substances are detected with improved sensitivity. Thus, it is easy to determine whether biological samples contain forensic toxicological substances, and data analysis times are substantially reduced. Analysis of Toxicological Substances in Whole Blood Using the Smart Forensic Database (1) 3. Creates Optimal MRM Methods Automatically The Smart MRM program creates MRM methods automatically. In multicomponent simultaneous analysis, it is difficult to configure the dwell, event, and loop time-measurement settings in the MRM program. Smart MRM, however, automatically determines the optimal time-measurement settings, and creates a high-sensitivity method. The MRM method is created based on the retention time information for target compounds, using the AART function. Analysis of Toxicological Substances in Whole Blood Using the Smart Forensic Database (2) Shimadzu has also released a new version of its LC/MS/MS Rapid Toxicology Screening System. For more information, visit: http://www.shimadzu.com/an/lcms/toxicology.html Remarks and Precautions 1. Shimadzu makes no warranty regarding the accuracy of information included in the database or the usefulness of information obtained from using the database. Comprehensive 2D Chromatography e-Series New Systems Enable Detailed Analysis of Structural Analogs and Other Complex Samples 2. Be sure to perform tests using standards to confirm qualitative and quantitative information obtained with the given system. Extensive support for creating MRM methods 3. To reliably identify registered substances using this database, measure samples using the instrument parameters specified in the method template files included in the product. 4. Combination with the GC/MS Forensic Toxicological Database in Simultaneous Scan/MRM Measurement 4. This database is for research purposes. It cannot be used for clinical diagnostic applications. Scan data obtained with simultaneous Scan/MRM measurements can be analyzed using the GC/MS Forensic Toxicological Database, which is used to screen for forensic toxicological substances. MRM data can be used for trace quantity analyses of toxicological substances often involved in poisonings, which are registered in the Smart Forensic Database, while the scan data can be used to screen for drugs of abuse using the GC/MS Forensic Toxicological Database, which includes many designer drugs. For Research Use Only. Not for use in diagnostic procedures. The new systems maximize the uppermost features of chromatography, separation performance, and detection, and achieve high-resolution analysis, even for structurally similar compounds. The e-Series consists of the Nexera-e LC×LC system and the Ultra-e GC×GC system. Dedicated ChromSquare software is used for data analysis. Features - Excellent performance for enhanced separation and high-speed analysis - Systems based on Ultra Fast Mass Spectrometry (UFMS) technology - Easy Analysis Note: ChromSquare is a product of Chromaleont S.r.l., Italy. iMScope TRIO Advanced Imaging Technology Platform Brings Together Innovative Mass Spectrometry and High Resolution Morphological Images Shimadzu’s New Simultaneous ICP Atomic Emission Spectrometers Achieve Stable Analysis with Low Operating Costs The iMScope TRIO is the world's first imaging technology that supports Featuring user-friendly software, a proprietary design, Eco mode, high-resolution morphological imaging from an optical microscope and enabling high-speed simultaneous analysis of multiple overlaid with molecular distribution images generated by high mass elements, the ICPE-9810 and ICPE-9820 improve throughput and accuracy mass spectrometry with a spatial resolution of 5 µm. reduce operating costs. - Global Leader in high spatial resolution mass spectrometry imaging - Lower operating costs thanks to eco mode - Integration of optical and mass spectrometry images - Faster rinse time and reduced memory effects increase analytical - High-level qualitative analysis via the IT-TOF function Sales area: all areas excluding North America throughput - Simultaneous acquisition for all wavelengths and easy reanalysis with ICPEsolution control software