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PSSM - 8 System

PSSM - 8 System

PSSM - 8 System

Product catalog summary
Overview: The PSSM-8 System by Shimadzu is an automated solid-phase peptide synthesizer designed for simultaneous multiple peptide synthesis. It is particularly useful for epitope mapping and structure-activity relationship studies, employing Fmoc chemistry to avoid hazardous chemicals and facilitate easy cleavage.
System Features:
  • Independent Channels: The system includes eight independent channels with disposable reaction vessels, washing ports, and micro-syringes, allowing for flexible peptide synthesis without cross-contamination.
  • Software Integration: Two software packages are available for synthesis calculation and operation control, enabling users to set synthesis conditions via a personal computer and store them on an IC-memory card for automated operation.
  • Efficient Synthesis: Capable of synthesizing 10 to 20 amino acid residue peptides in 1-1.5 days, with separation and characterization completed in under 3 days.
  • Flexible and Adaptable: The system supports various peptide lengths and chemical protocols, adaptable to future developments in chemistry.
  • Cross-Contamination Prevention: Equipped with separate nozzles for solvent removal and reagent needles to eliminate cross-contamination.
  • Simultaneous Cleavage: Reaction vessels are used directly for cleavage, minimizing mechanical loss, especially in small-scale synthesis.
Applications: The PSSM-8 is suitable for synthesizing neuropeptides, hormones, antigens, and for rapid evaluation of chemical conditions. It supports the synthesis of high-quality peptides for NMR studies, pharmacological research, and antigen preparation.
Technical Specifications:
  • Synthesis Scale: 10-100mg (5-50μmol/Lane)
  • Coupling Time: 1 hour per cycle
  • Reaction Vessel: Disposable syringe tube type with filter, 2.5 ml
  • Mixing Method: Nitrogen gas bubbling
  • Reagent Delivery: Syringe (50-900μl) x 8 lanes
  • Dimensions and Weight: W970 x D630 x H610 mm, 105kg
  • Power Requirements: 200-240Vac, 50/60Hz, 2A or 100-120Vac, 50/60Hz, 3A
Conclusion: The PSSM-8 System is a versatile and efficient tool for peptide synthesis, offering high flexibility, ease of use, and the ability to produce high-quality peptides in various quantities. It is supported by a comprehensive software package and is designed to meet the needs of researchers in peptide chemistry and related fields.
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Catalog excerpts

PSSM - 8 System-1

Shimadzu Automated solid-phase peptide synthesizer in simultaneous multiple mode

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PSSM - 8 System-2

Automated solid-phase peptide synthesizer in simultaneous multiple mode PSSM-8 System

 Open the catalog to page 2
PSSM - 8 System-3

PSSM-8 System S himadzu Automated solid-phase peptide synthesizer in simultaneous multiple mode The PSSM-8 System is a bench-top, automated, simultaneous, multiple solid-phase peptide synthesizer. It was developed through a combination of our considerable, practical exper iences in peptide chemistr y and our exper tise in instr umentation hardware and software. Multiple, simultaneous preparation of different peptides is in great demand. Using the PSSM-8, high-quality peptides can be routinely synthesized. These are very useful for epitope mapping studies and for studying structure-activity relationships....

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PSSM - 8 System-4

You can obtain high-quality peptides in any quantity: sim The PSSM-8 is extremely flexible and adaptable to different chemistries and protocols. The rapid synthesis of neuropeptides, hormones and antigens is efficiently carried out. This is very useful for the rapid evaluation of chemical or reaction conditions. It speeds the search for peptides such as epitopes or for potent structures, inhibitors, agonists, or antagonists. 1. EFFICIENT AND RAPID SYNTHESIS With the PSSM-8, 10 to 20 amino acid residue peptides can be prepared in 1-1.5 days, which is followed by simultaneous cleavage. You can...

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PSSM - 8 System-5

tity: simultaneously, routinely, and economically. A pp lic a tio n s Synthesis of Leu-Enkephalin using 8 channels (same peptides, same chemistry) Reverse-phase HPLC of crude peptides after cleavage Column: SynProPep RPC18 (4.6 x 250 mm), Eluent: 0.01N HCI/CH3CN = 85/15 - 55/45 (30 min), Flow rate: 1.0 mL/min, Absorbance: 210nm Synthesis of Neuromedin U consisting of 25 amino acids Reverse-phase HPLC of crude peptides after cleavage peptide Column: SynProPep RPC18 (4.6 x 250 mm) Eluent: 0.01N HCI/CH3CN, 85/15 - 55/45 (30 min) Flow rate: 1.0 mL/min, Absorbance: 210nm Synthesis of PACAP fragments...

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PSSM - 8 System-6

Setting up the conditions for peptide syn Using a personal computer, the conditions for synthesis can be easily set up with the specialized software for simultaneous multiple preparation. Following the MENU on the display, the chemistry (5 chemistries are installed), amino acid sequence, resin type, scale of the synthesis, double coupling or capping protocols, etc. can be entered and stored in a memory card with the memory card drive (BMD-1). By loading this card into the PSSM-8, the synthesizer can be automatically controlled without tying up your computer. You can use the computer for other...

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PSSM - 8 System-7

Amino acid derivative registration window Easily register new amino acid derivatives. By loading the memory card, the synthesis can be Our total support for peptide studies SynProPep® Package Synthesis System for Proteins & Peptides • Polymer Supports • Amino Acid Derivatives • Coupling Reagents Efficient Synthesis Automated Synthesizer Isolation Purification Analysis HPLC System SynProPep Columns • Structure-Activity Relationship • Synthetic Vaccine • Epitope Mapping (Peptide Antigen) • Protein Engineering • Hormone / Neuromodulator • Pharmacology / Physiology Analyses for Structure Determination...

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PSSM - 8 System-8

synthesis unit Memory card drive (BMD-1) Septum for reagent reservoir 60 Amino acid vessel 500 Septum for washing port 10 Insert for reaction vessel 8 Teflon tube for drain 2m Technical specifications Automated Simultaneous Multiple Peptide Synthesizer, PSSM-8 system Coupling time 1 h/cycle (standard protocol) Reaction vessel I Disposable syringe tube type with filter, Amino acid vessel Tube with safety lid lock, 2.0 ml Reagent reservoir Synthesized lanes Mixing method Reagent delivery Amino acid station Reagents station Operation panel Flatboard keyboard Memory card slot Ambient temperature...

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