SCIENCE THAT NURTURES WELLNESS InterOssAnorganic Cancellous Bone Granules Biomaierial* InterOss Anorganic Cancellous Granules

Anorganic Cancellous Bone Granules InterOss® is a natural hydroxyapatite bone grafting material for use in dentistry. Made from a proven multi-step purification process which leaves only a bone composition, it is a highly purified osteoconductive material for bone regeneration. Having an interconnected network of macro and micro pores and large inner surface areas that provides an ideal environment for cell attachment, InterOss® is chemically and structurally comparable to mineralized human bone. It is available in sterilized granule form and is dedicated for single uses. Highly purified bone...

Features & Benefits (cont’d) Osteoconductive A preclinical trial was conducted to treat 54 mandibular critical-sized alveolar ridge defects in 27 canines. The study confirmed InterOss®’ osteoconductivitiy as it was clinically and histologically successful in forming new bone. At 4 weeks: Residual material with some woven bone formation (N) was observed. At 8 weeks: A significant amount of new bone formation (N) was observed. At 12 weeks: A mixture of mature and woven bone formation (N) was observed. A Comparison Study with Bio-Oss® Percent Bone (%) Percent Bone by Area (BA/DA) While not statistically...

Application & HandlingHydration InterOss® can be hydrated in blood or sterile saline solution. Ensure that the grafted site is securely closed with the soft tissue free of tension. Healing time depends on the patient, nature and the size of the defect site and thus must be determined by the clinician based on the initial diagnosis. For a safe re-entry, it is recommended to let the surgical site heal for at least six months to ensure the graft material has been integrated properly. The long-term stability of InterOss® coupled with the biological potential of allograft may yield enhanced bone regeneration....

Alveolar ridge augmentation through guided bone regeneration Dr. Byung Do Ham Kainos Dental Clinic South Korea Patient was missing tooth number 42. It was determined that the missing tooth should be restored byimplant restoration. InterOss® actively induced new bone formation, and implant placement surgery was successful. Decalcified section showed a trabecular bony network with thick osteophyte formation. Pre-operative view. A view of the bone defect. InterOss® placement. Membrane placement and immediate post-operative view. Post-operative view at 5 months. Implant placement. Post-operative...

Alveolar ridge augmentation through guided bone regeneration Dr. Byung Do Ham Kainos Dental Clinic South Korea Patient was missing tooth number 46. It was determined that ridge augmentation was needed for implant placement. After 5 months of healing, implant placement surgery was performed and successful. Decalcified section showed active new bone formation on InterOss®. As InterOss® gradually resorbed, it subsequently induced osteogenic effect for excellent bone formation. Pre-operative X-ray. A view of the bone defect. InterOss® placement. Membrane placement and immediate post-operative view....

Vertical ridge augmentation through sinus floor elevation Dr. Byung Do Ham Kainos Dental Clinic South Korea Patient suffered from missing tooth number 15 and 16. It was determined sinus augmentation was necessary for implant placement surgery. Decalcified section showed active new bone deposition on the xenogeneic graft bone (InterOss®). This graft lesion was clearly competent with favorable bony remodeling, still undergoing further new bone deposition. Pre-operative X-ray and view. Exposure of the defect site. Sinus cavity exposure. InterOss® placement. Membrane placement. Immediate post-operative...

SigmaGraft SCIENCE THAT NURTURES WELLNESS BIDMATE RIALS SigmaGraft®, based in Fullerton, , California, USA, collaborates with the world's leading clinicians and researchers to innovate products and build clinical experience. Our products are registered and sold worldwide, and they include bone grafting products for bone regeneration, membrane products for tissue regeneration, and more. 575 Sally Place Fullerton, CA 92831 United States www.SigmaGraft.com 1438 E. Valencia Dr. Fullerton, CA 92831 United States Asia Branch 13-8, Woldong-ro 15beon-gil, Siheung-si, Gyeonggi-do (104-5) South Korea