Automated Filling Line

Automated Filling Line for commercial production The Crystal™ L1 Filling Line enables the scaling-up strategies of biopharmaceutical companies globally. This automated equipment is designed to perform filling of stability batches, clinical batches and mid-size production. Fully compliant with cGMP requirements and CFR 21 part 11, the Crystal™ L1 Filling Line is able to process the complete range of the ready-to-fill AT-Closed Vial® from 1ml to 50ml. This automated Filling Line can fill up to 500 AT-Closed Vial® per hour, filling an entire AT-Nest™ without any manual intervention. The Crystal™...

The Crystal™ L1, when combined with an active Restricted-Access Barrier System (RABS), provides the enclosed controlled environment for aseptic filling process with a minimal footprint. —> To be installed in a Grade B environment —> Reduced footprint —» CFR 21 Part l1 compliant —> AT-Port™ for fluid transfer —> Active Laminar Air Flow (LAF) or mousehole for material transfer —> Installed and qualified in one week Relying on the Aseptic Technologies single-use materials and the AT-Closed Vial® of various formats, the Crystal™ L1 in RABS provides flexibility in cGMP fill & finish operations, while...

Highest sterility assurance Combining Aseptic Technologies Filling Line and SKAN isolator, the Cellana L1 allows aseptic processes to take place quickly and safely within the highest sterility conditions. To be installed in a Grade C or D environment Integrated automated skanfog H2O2 decontamination system CFR 21 Part 11 compliant AT-Port™ for fluid transfer SARA (SAfe and RApid decontamination airlock) for material transfer The Aseptic Technologies L1 Filling Line is an automated filling line for ATClosed Vial® with high filling accuracy, which reduces contamination risks with its unique AT-Closed...

Quick, safe and easy fill & finish The bulk product container, remaining outside of the RABS or isolator, is connected to the operating area with the AT-Port™ System, the aseptic liquid connector. Through the selected material transfer system of the equipment, the nested ready-to-fill AT-Closed Vial®, and other single-use material, are introduced to the critical area, where prepared for operation. The operator positions the AT-Nest™ and prepares the fluid path, rendered possible with the AT-Filling Kit™. Activated from the HMI, the clean 6 axis robot then initiates the closed vial filling process....

SKAN AG Kreuzstrasse 5 4123 Allschwil, Switzerland +41 61 485 44 44, [email protected] SKAN Stein AG Industriestrasse 3 4332 Stein, Switzerland +41 62 885 03 00, [email protected] SKAN Deutschland GmbH Nickrischer Straße 2 02827 Görlitz/Hagenwerder, Germany +49 358 223 789 0, [email protected] SKAN US, Inc. 7409 ACC Blvd., Suite 200 Raleigh, NC 27617, USA +1 919 354 6380, [email protected] SKAN Japan 5194-61 Katsuren-Haebaru Uruma-shi Okinawa 沖縄県 904-2311, Japan 日本 +81 98 934 9922, [email protected] © 2024 – Aseptic Technologies S.A. – Brochure Crystal™ L1 – V1.4 Aseptic Technologies S.A. reserves...