Syncera * Powered by smfth&nephew ANTHEM Total Knee System Value Brief 07148 V1 ANTHEM Total Knee System Value Brief 10.16.indd 1

The ANTHEM™ Total Knee System is designed to meet the needs of all stakeholders. With a continued dedication to innovation, the ANTHEM Total Knee System drives enhanced value to all facets of the healthcare system, providing tangible advantages for arthroplasty surgeons, patients and healthcare providers SURGEON The ANTHEM Total Knee System builds upon established design fundamentals, while incorporating advanced features to improve implant fit, enhance the surgical experience, and reduce clinical compromise. After extensive research in conjunction with global experts, the ANTHEM design has been...

Improving anatomic implant fit • Enhanced femoral and tibial anatomic implant fit for all patients • Anthropometrically optimized low profile femoral anterior flange to reduce incidence of overhang • Bone conserving femoral PS box design preserving intercondylar notch bone stock • Anatomic asymmetric tibial baseplate design with shorter, medialized tibial stem to suit a wider range of anatomies Advanced technology • Equivalent implant tibio-femoral kinematics and articulation to the clinically successful GENESIS II design 2'3'4 • Patella Friendly S-curve funnels patella to facilitate tracking...

References 1. ANTHEM AdAM (Anatomical Data Mining) CT data utilsing Caucasian, Chinese, India, Middle Eastern and African data sets . Data on file 2. Smith & Nephew, Inc. ANTHEM™ PS Total Knee System: 510(k) Summary. Pg E2-1-2 3. Bourne et al. Survivorship of the Genesis II Total Knee Arthroplasty at a Mean of 15 years. COA poster presentation. 2014. 4. Victor et al, Total knee arthroplasty at 15–17 years: Does implant design affect outcome? International Orthopaedics; 2014. 38:235–24 5. Wei, David H., et al. “Improving Value in Musculoskeletal Care Delivery.”The Journal of Bone & Joint Surgery 97.9,...