MaSTR software features a rapid and transparent approach to Probabilistic Mixture Analysis which utilizes your forensic acumen in an easy-to-use Windows® environment for research, validation and casework applications. Server based MaSTR software is very cost effective, includes two simultaneous user licenses, and automatic queuing of multiple analyses. MaSTR software was designed following The Organization of Scientific Area Committees for Forensic Science (OSAC) and Scientific Working Group on DNA Analysis Methods (SWGDAM) probabilistic guidelines and published probabilistic approaches (Taylor,...

Validated Contact [email protected] for a copy of the validation study performed by Dr. Michael Adamowicz. Dr. Adamowicz is currently Director of the Forensic Science program at the University of Nebraska and was previously a faculty member and forensic science program coordinator at the University of New Haven, Henry C. Lee College of Criminal Justice & Forensic Sciences and a member of the SWGDAM Mixture Committee developing / writing mixture analysis guidelines. Contact [email protected] to arrange a trial version and introductory training for your laboratory. SoftGenetics will provide...

Flexible Capacity Unique System Design -- MaSTR probabilistic genotyping software makes efficient use of the lab computer resources. With Server-client based technology, processing is done on the server and multiple clients can review results and send new jobs (Figure 1). Each user sets up and sends analysis jobs from existing client computers. Expedited cases can be moved to the front of the queue by laboratory management. The high-speed server processes data from the queued jobs submitted by client computers. The design is flexible – labs with a lower caseload may opt to install server/database...

High Speed with minimum computer specifications Table 1: Provides examples of analysis times for simple to complex mixtures; processing two jobs at a time on a server with the minimum specifications. Figure 2: The capacity of MaSTR software can easily be increased with your computer hardware. The number of cores increases the capacity, not the speed.

Technology MaSTR software’s unique, easy-to-use interface enables analysts to create and submit mixture analysis jobs in minutes. The server-client configuration provides flexibility and lowers costs by performing the analyses on a dedicated computer, freeing up the analyst’s time and computer for other tasks. ● Provides a framework for growth: ○ MaSTR software easily adapts future chemistries by importing new or updated panels (Figure 3) ○ Upgrade statistical approach without changing software version ● Utilizes the laboratory’s unique data set to “train” the software (Figure 4) ● After validation,...

Flexibility Easy import of new panels, allele frequencies to be used in analysis, and staff profiles to an elimination database. MaSTR software automatically checks the project’s results with the database to flag potential contamination. Figure 3: Simple, drop-down menus enable labs to update panels with new loci, population allele frequencies, and staff profiles to the elimination database. Customize with a Protocol Data Set -- giving MaSTR software context to evaluate mixtures produced following the laboratory SOP Figure 4: Protocol data sets – replicates of single source dilutions produced...

Figure 5: Casework analyses are easily submitted using the dropdown menu to select the validated: • Protocol Set, Population Allele Frequency and Model • Select the appropriate Coancestry adjustment (no adjustment to assume Hardy Weinberg equilibrium, NRCII Recommendation 4.1 or NRCII Recommendation 4.2. • Enter the appropriate theta value if a coancestry adjustment is selected. • Name the job and enter any comments • Specify the number of contributors • Select the mixture .txt file (containing all called peaks and peak heights), .txt file of person of interest genotype(s), any known contributor...

Customized Reporting Each pdf report contains a cover page with the institution name and logo, a table of contents and the fields selected by the analyst. PDF and Print reporting Cover page contains: ● Laboratory Logo ● Laboratory Name ● Name of the project ● Job overview

Efficient reporting: Include the sections of the project that are pertinent to the case. Exclude any of the support documentation that was not required for the analysis. Flexible Technology Provides a Framework for Growth MaSTR software provides flexible technology that allows custom modeling and development. The software provides a framework that empowers both forensic analysts and researchers. As new models are developed by researchers, the model can be tested and validated within MaSTR – when validation is completed, the model is locked in for casework. The models can be expanded; the software...

REQUEST a MaSTR software time limited trial and introductory training [email protected] Computer Specifications Computer Requirements - Server ● Minimum Specs (complex mixtures may not run) ○ 4-core CPU ○ 16 GB of RAM ○ Solid-State Drive (SSD) for storage ○ 64-Bit OS running Oracle VM VirtualBox with virtualization enabled ● Suggested Specs ○ 8-core CPU (or better) ○ 32 GB of RAM (or better) Computer Requirements - Client ● Clients connect to and interact with the server on the internal network using a web-browser - either Google Chrome v56 (or higher) or Mozilla Firefox

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