Human ROS1 Fusion Gene Detection Kit (Real-Time PCR assay) LUNG CANCER AND GENE FUSION Lung cancer is the most common primary malignant tumor of the lungs, with the fastest growing incidence and mortality rates, making it one of the most threatening malignancies to human health and life. The ROS1 gene belongs to the tyrosine kinase insulin receptor gene, which is related to cell growth, proliferation, differentiation, and survival. Fusion of the ROS1 gene can continuously activate the ROS1 tyrosine kinase domain and downstream signaling pathways such as JAK/STAT, PI3K/AKT,RAS/MAPK leading to the development of tumors. Approximately 1-2% of NSCLC cases have ROS1 fusion. Crizotinib has significant anti-tumor activity in patients with advanced ROS1 fusion-positive NSCLC. DETECTED GENES Reaction tube Gene partners and Exon

PRODUCT INFORMATION Product Name Pack Size Instruments Validated Sample Type Human ROS1 Fusion Gene Detection Kit Tumor tissue, Pleural and Ascites DETECTION SIGNIFICANCE ﹡Select patients for the targeted treatment of NSCLC based on the presence of ROS1Positivity. ﹡Crizotinib has significant anti-tumor activity in patients with advanced ROS1 positive NSCLC. FEATURES & ADVANTAGES Accuracy and Reliability: Use pre-load PCR tube to effectively avoid cross-contamination. Great Versatility: Validated on the most common qPCR machines with stable results. Easy Operation: The process is standardized...