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Identification And Detection of Invasive Fungal Species in Lung Tissue (Nucleic Acid Mass Spectrometry Method) With the widespread use of hematopoietic stem cell transplantation, solid organ transplantation, immunosuppressive agents, chemotherapy drugs, and various invasive procedures, the incidence of invasive fungal infections in the lungs is gradually increasing. Patients with pulmonary fungal infections often lack specific symptoms, and early diagnosis is challenging. The condition is easily masked by underlying diseases, leading to misdiagnosis, missed diagnosis, and delayed treatment, resulting in a high mortality rate. Therefore, accurate detection of invasive fungal infections in lung tissue is crucial for the diagnosis and treatment of the disease. DETECTION CONTENT strain name Analysis Project strain name Analysis Project strain name Analysis Project Candida albicans Sporothrix schenckii Candida portuguese Penicillium marneffei Blastomyces dermatitidis Candida guilderii Blastomyces gizii Candida parapsilosis Histoplasma capsulatum Candida tropicalis Actinomyces clothenii Candida Dublin Candida krusei Candida glabrata Cryptococcus neoformans Sporotrichum globosa Cryptococcus gattii Sporotrichum brasiliensis DETECTION METHOD Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry (MALDI-TOF-MS) is a novel technique used for the analysis of biological molecules. It involves the formation of a thin co-crystallized film by irradiating the sample with a laser in the presence of a matrix. The matrix absorbs energy from the laser and transfers it to the biological molecules, causing their ionization. The ionized molecules are then accelerated through a flight tube by an electric field, and their time of flight to the detector is used to accurately determine their molecular weight, allowing for precise identification and separation of biomolecules.
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PRODUCT INFORMATION Product Name Human Lung Tissue Invasive Fungal Species Identification Kit nucleic acid mass spectrometry Pack Size Instruments Validated Sample Type MassARRAY®DNAMass Spectrometry Gene Analysis System paraffin embedded tissue DETECTION SIGNIFICANCE Accurate identification of the 30 common invasive fungal species in clinical settings provides a clear understanding of the pathogenic organisms and offers a scientific basis for anti-infective treatment. FEATURES & ADVANTAGES 1. Technological Advancement: The analysis combines PCR technology to analyze the nucleic acid...
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