Using Star-Oddi’s loggers comes with the benefit that each logger can be sterilized and reused for as long as the battery lasts. However, as Star-Oddi’s loggers contain electronics, not all sterilization techniques are suitable; this includes techniques where temperature exceeds 60°C, unless otherwise stated. Star-Oddi loggers are shipped non-sterile. High temperature methods, such as autoclaving, and radiation methods, such as gamma radiation, are not suitable to sterilize Star-Oddi’s loggers. When using Star-Oddi’s loggers in animal models it is recommended that the loggers are sterilized rather than disinfected. An important difference between these two methods is that sterilization kills all viable microorganisms, while disinfection only reduces their numbers. When using sterilization solutions it is important to handle the product correctly after the sterilization procedure. Do NOT use: Gamma sterilization or high temperature sterilization such as autoclave sterilization, these methods will have irreversible effect on the batteries and electronics inside the logger. In this document we outline some of the suitable sterilization methods for Star-Oddi’s products. Ethylene Oxide (ETO) Sterilization • Prevents microbial reproduction by reacting with amino acids, proteins and DNA. • Consists of five stages: evacuation with humidification, gas introduction, exposure, evacuation, and air washes.

• Duration: around 2 V2 hours, excluding aeration. Aeration can be either mechanical, which takes 8-12 hours at 50-60°C, or passive, which can take seven days. • Temperature conditions range from 30-60°C. • Warning: ETO is highly flammable and carcinogenic. • Acts as an oxidizing agent by reacting with the cell membrane of microbes, and other cellular constituents. • Consists of five stages: preconditioning with humidification, conditioning, generation and delivery of chlorine dioxide gas, exposure and aeration. • Duration: around 2V2 hours, including aeration time. • Temperature during the process:...