Accurate and stress-free measurements for short and long term studies Ultra small implantable loggers Logging Life Science

High performance, small size Available parameters in each size Physio loggers Choose parameters: Heart rate Activity Temperature Heart rate Activity Temperature Heart rate Activity Temperature Activity and Temperature loggers Choose parameters: Activity Temperature Activity Temperature Activity Temperature

Advantages at a glance Minimally invasive, simple to set up and to implant Stress-free accurate measurements Biocompatible and reusable Long battery life

Time [Days] Circadian rhythm recorded as core body temperature (green) With sampling interval of 10 min at room temp Outside ranges available upon request

Measure heart rate and body temperature simultaneously. Apply to a variety of studies including circadian rhythm, stress response and baseline metabolic studies. The heart rate measurements are derived from a leadless single channel ECG. The electrodes are part of the housing making the loggers easy to implant and explant. The loggers can measure heart rates ranging from 5 bpm to 1022 bpm and include an option to record extended ECG records for periods where slow heart rates are expected. With sampling interval of 10 min Outside ranges available upon request

Temperature and Activity data from a Baboon during an infection study showing fever and lethargy. Activity levels are displayed as hourly average of AvgEA values. For 1Hz sampling requency over 1 min, sampling interval 1-20 min, activity and temperature recorded simultaneously If all parameters are recorded simultaneously Outside ranges available upon request

Time [Days] Data recorded with DST milli-HRT-ACT in Cynomolgus Macaque during an vaccine efficacy trial. Data for temperature, heart rate and activity are shown as hourly averages (± SD). * For sampling interval of 2-20 minutes; ECG sampled at 600Hz, Activity 1Hz over 1 minute. ** Outside ranges available upon request *** If all parameters are recorded simultaneously

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