8 reasons why hospitals are choosing the Passio Pump Drainage System for their malignant pleural effusion and malignant ascites patients passioPump Drainage System passio Pump Drainage System Passio evacuates fluid at Mr exponentially lower vacuum levels (-45 to -70 cmH20) than the competitor devices* Passio's digital handheld control unit offers control of flow with the simple push of a button. Defined flow rate determined by selecting Speed 1,2,3 or 4. Cel pack in collection bag turns Mn drained fluid into gel to reduce risk of exposure during disposal. Skin prep wipe in redressing kit creates a barrier between patient's skin and adhesive dressing to minimize skin breakdown. Smaller packaging with same number of units saves space in storeroom and on hospital floors. Handheld control unit screen displays volume drained and operation speed. There is a greater risk for injury with exposure to high levels of negative pressures. Lower pressures are less likely to cause harm to the patient. Pressures greater than -200cmHzO have been shown to cause damage to lung tissue." Training on Passio handheld is simple and relatable to the caregiver and/or patient. It also requires minimal hand strength which is not the case for the roller clamp or bulb. Fixed speed and flow rate vs. a variable system provides confidence that the therapy is going to be the same rate each time, providing for peace of mind to the patient Minimizes the risk of fluid leak and exposure if the bag is punctured in trash. No other device offers this feature. This patient population has delicate skin and the dressing is replaced after each drainage. Protecting the skin minimizes risk of skin breakdown and additional treatment cost Less storage space utilized in hospital and patients home and less cost of freight to hospital. IT'S TIME TO TAKE CONTROL OF YOUR THERAPY Simple to use handheld control unit \*Wi places control of the therapy into the hands of the patient Fixed speed is easily communicated when multiple care givers are performing therapy and calculated volume minimizes room for error in visual confirmation. Patient has control over their therapy and can speed up or slow therapy as they see fit with the simple push of a button. Designed inBELGIUM DISTRIBUTED BY SYNDEO Medical

The world’s handheld digital drainage system for patients diagnosed with Controls both fluid flow and vacuum. If pump is engaged, vacuum is generated. When pump is paused - no vaccum Competitor A Manually control fluid flow by raising or lowering collection bag and squeezing Competitor B Manually control fluid flow (not vacuum) by applying roller clamp Complete Control Over Therapy• Passio allows therapy to be paused at any time • 4 speeds allowing user to control speed of flow*: +Approximate rates Technological Benefits • LCD displays volume of fluid collected • Warning at Handheld Control Unit...