SUCCESS STORY Corin & Synopsys Simpleware Streamlining Orthopedic Surgical Planning “ The Simpleware technology is integral to our production system. We have always had a very good relationship with Synopsys and regularly are able to reach out for their support. The introduction of Simpleware’s Custom Modeler has not only reduced segmentation time but also enabled faster training of the production process to new staff. Alicia Miller, Production Engineering Manager, Corin Highlights • Simpleware software enables Corin to process 3D image data for its OPS system • Recent updates in the deployed Simpleware Solution, via Simpleware Custom Modeler’s AI tools, have made this process more streamlined and efficient • OPS technology has been used in 20,000+ procedures Introduction Total hip arthroplasties (THAs) that include patient-specific implants, guides and surgical plans have been rapidly increasing in frequency over the past decade. This increase is creating more demand from patients, and growing pressures on clinicians and medical device companies to deliver and deploy their patientspecific products quickly and safely. In this context, patient-specific data from MRI and CT scans can be used to create 3D models for orthopedic cutting guides, implants, and pre-surgical plans. The primary challenge when optimizing patient-specific workflows is to ensure speed, efficiency, and scalability, while also maintaining clinical accuracy and regulatory compliance. When creating 3D models of a patient’s anatomy, it is typically left up to a group of highly-trained and valuable biomedical engineers to complete this task; it is therefore particularly important for a company to deploy a highly efficient and scalable process, to free up engineering time, save on costs, get to market faster, and maintain the quality of the final output.

Synopsys and the Corin Optimized Positioning System (OPS) group have been working together for over 10 years to develop and streamline their OPS workflow, which is designed to optimize stability, longevity, biomechanics, and patient outcomes for THAs over time. This relationship has grown from a few licenses of the Synopsys Simpleware software platform to a deeply integrated and customized solution for different stages of the OPS workflow where it has been deployed to over 20,000 patients. This has been a longterm relationship where the Simpleware group has focused on aligning to the vision of...

Workflow Automation Typical Simpleware processing time savings for Hip, Knee and Ankle combined (segmentation and landmarking) when compared to using off-the-shelf software with no customization. • Using non-AI scripting plugins*: Reduced time by 65% per case Using original Custom Modeler plugin: Reduced time by 80% per case ~2/3 of time is computer time (no human interaction) and remaining is tidy up time Using enhanced** Custom Modeler plugin: Reduced time by 94% per case ~2/3 of time is computer time (no human interaction) and remaining is tidy up time * Plugins developed using the Simpleware...

Next Steps As the use of patient-specific workflows for device design and surgical planning grows into different anatomies and medical device applications, having access to flexible and customizable end-to-end solutions like Simpleware Custom Modeler will be crucial to future innovation and growth for Medical Device companies. Looking to the future with Corin specifically, there are many more challenges that the Simpleware and OPS teams may tackle when it comes to optimizing patient-specific data and virtual surgical planning. The goal is to have the fastest turnaround time without compromising...