TECHNICAL DATASHEET Simpleware AS Ortho Release Version T-2022.03 March 7, 2022 Ankle CT Segmentation and Landmarking – Anterior Superior Iliac Spine (left and right) • Anatomy specific automated segmentation tool for the ankle – Posterior Superior iliac Spine (left and right) • Automatic segmentation suitable for use on CT scans – Greater Trochanter (left and right) – Lesser Trochanter (left and right) – Pubic Tubercle (left and right) – Femur Head (left and right) – Tibia • Landmarks placed on identified anatomy: – Ankle center – Fibular notch – Malleolus (lateral, medial) • Automatic ROI detection within larger extent scans • Option to retain all bone fragments Hip CT Segmentation and Landmarking • Anatomy specific automated segmentation tool for hip or pelvis region • Automatic segmentation suitable for use on CT scans • Produces masks for: • Automatic ROI detection within larger extent scans • Option to retain all bone fragments Knee MRI Segmentation and Landmarking • Anatomy specific automated segmentation tool for the knee • Automatic segmentation suitable for use on MRI scans (PD weighted Sagittal/Coronal and T1 Coronal and T2 Sagittal) • Produces masks for: – Femur and associated cartilage – Tibia and associated cartilage – Patella – Fibula • Landmarks placed on identified anatomy: – Femur Condyles (lateral and medial) – Femur Epicondyles (lateral and medial) – Proximal Femurs – Tibia Condyles (lateral and medial) • Landmarks placed on identified anatomy: – Tibia Intercondylar Eminence • Automatic ROI detection within larger extent scans Simpleware AS Ortho (Auto Segmenter for Orthopedics) provides anatomyspecific, automated segmentation tools for orthopedic data using Machine Learning (ML) al

Knee CT Segmentation and Landmarking • Landmarks placed on identified anatomy: • Anatomy specific automated segmentation tool for the knee • Automatic segmentation suitable for use on CT scans – Malleolus (lateral, medial) – Humerus bicepital groove – Humerus bicipital groove – Humerus greater tuberosity – Humerus head centre – Fabella (where present) – Humerus lesser tuberosity • Landmarks placed on identified anatomy (for left and right knees): – Scapula acromion – Scapula coracoid – Femur posterior condyles (lateral, medial) – Scapula glenoid cavity – Femur epicondyles (lateral, medial) –...