XT-4000i * Fluorescence flow cytometry for high quality haematology analysis * More than blood alone – a dedicated mode for body fluids * Extended Diagnostic Capabilities on board (IG, Ret, Ret-He, IRF) * Sysmex Gold standard reticulocyte technology for monitoring erythropoietic status (Ret, Ret-He, IRF) * Online QC, optimised workflow, cost-efficient reagent consumption XT-4000i – Outstanding diagnostics plus dedicated body fluid analysis The XT-4000i really is an outstanding haematology analyser. Using Sysmex’s unique fluorescence flow cytometry, the analyser looks at RNA/DNA content, cell size and inner cell complexity rather than just cell size. This generates remarkably accurate results and a superb WBC differential. For those who need special capabilities, the XT-4000i has a separate, dedicated true body fluid mode. It has Sysmex’s famous gold standard reticulocyte technology on board as standard for monitoring erythropoietic status (Ret, Ret-He, IRF), as well as true quantitative IG counting instead of mere flagging. And it is particularly precise for RBC and PLT parameters thanks to hydrodynamic focusing. The analyser is practical and can be adapted to your own particular workflow. You will appreciate its cost-effective reagent consumption, and the fact that you can adapt the diagnostic sensitivity to your own laboratory needs through its unique Q-flags. You can also attach it to our network communication system for online quality control. Dedicated body fluid mode Analysing body fluids (BF), particularly cerebrospinal fluid (CSF), requires great focus from the laboratory since the specimen material is so delicate. This, and the many manual preparatory steps, mean analysis results tend to vary greatly, and so impair the information that is so crucial for clinicians and their patients. The XT-4000i provides a count for white and red blood cells found in CSF and other body fluids, as well as a total nucleated cell (TNC) count. This count can include macrophages, erythrophages, tumour cells, mesothelial cells and plasma cells, if present. Thanks to our expertise in cell counting technology, you can now count and classify particles even in low concentration ranges. You no longer have to specially prepare the sample material. Simply hold the sample tube under the instrument’s aspiration needle and it does the cell counting for you automatically. True reticulocyte count Using fluorescence flow cytometry, reticulocytes can be distinguished from mature red blood cells and white blood cells. You can reduce the interference between these cells to a minimum and even distinguish and quantify mature and immature reticulocytes. This leads to far more accurate results. Anaemia is often underestimated as a functional condition of red blood cells. But only the combined information provided by quantity- and quality-related reticulocyte parameters provides the whole picture behind anaemia diagnosis. Design and specifications may be subject to change due to further product development. Sysmex Europe GmbH, Bornbarch 1, 22848 Norderstedt, Germany, Phone: +49 (40) 527 26 0, Fax: +49 (40) 527 26 100 www.sysmex-europe

The XT-4000i can deliver this information as standard. Compared to the haemoglobin value or other RBC parameters, the RET-He value and parameter combinations enable significantly faster control during iron and/or erythropoietin therapy. True immature granulocyte count To increase your analytical possibilities, your XT-4000i offers a classic 5-part differential and a true immature granulocyte (IG) count, with far superior clinical utility than the flagging offered by other technologies. IG supports the quick detection of inflammation and infections, and lets you monitor treatment. It also means...

Diagnosis of MDS (NEUT-X) Extended red blood cell analysis Efficiency evaluation of erythropoiesis (RET-He, IRF, RPI) Therapy monitoring with anaemia of chronic diseases (RET-He) Differential diagnosis of iron deficiency anaemia, haemolytic anaemia or thalassaemia (RET-He, %HYPO-He, %MicroR, FRC, RBC-He, Delta-He) Technology fluorescence flow cytometry: WBC DIFF, IG, RET, IRF, PLT-O DC sheath flow: PLT, RBC, HCT; SLS method (cyanide-free): HGB Diagnostic parameters whole blood mode: WBC, RBC, HGB, HCT, MCV, MCH, MCHC, PLT, RDW-SD, RDW-CV, PDW, MPV, P-LCR, PCT, NEUT%, LYMPH%, MONO%, EO%, BASO%,...