Innovation, Synergy, Efficacy, Evolution… serving surgeons.

Innovation Tecres research laboratories developed the first Vancomycin and Gentamicin loaded bone cement. is the ideal solution for the fixation of antibiotic-loaded spacers and prosthetic components during revision surgery due to infections caused by resistant micro-organisms. MRSA (Methicillin resistant Staphylococcus aureus) and MRSE (Methicillin resistant Staphylococcus epidermidis) infections, in particular, continue to present a serious, yet common problem. Vancogenx provides surgeons with the ideal solution for the treatment of these complex cases. S. aureus: percentage of isolates clinically...

Synergy Vancomycin and Gentamicin • Have a synergic action as their antibacterial efficacy is more potent when they are used together. (1, 2, 3) • Boast a spectrum of action covering approximately 90% of the pathogens commonly isolated in orthopaedic infections.(3, 4) • Is the most commonly used and widely reported combination when bone cement is utilised in cases of concomitant treatment of infections.(5, 6, 7) Spectrum of action: microbiological efficacy Gram+ Staphilococci MET-S Staphilococci MET-R Pathogens isolated in prosthetic infections 50 Coagulase-negative Staphilococci Staphylococcus...

Efficacy Vancogenx In vitro studies have shown that proliferation. Vancogenx exerts an anti-adhesion action by inhibiting bacterial Bacterial adhesion S. aureus (MR-GR-VR) VRSA Very intense S. epidermidis (MR-GR) S. haemolyticus (MR-GR) S. hominis (MR-GI) Good M = Methicillin G = Gentamicin V = Vancomycin S = Susceptible I = Intermediate susceptible R = Resistant The chart shows the adhesion of clinical isolates to PMMA loaded with Gentamicin, Vancomycin and a Vancomycin-Gentamicin combination (Vancogenx). Use of the Vanco-Genta combination prevents bacteria from adhering to the PMMA(3) ■ as...

Evolution Vancogenx-Space devices are the exclusive preformed spacers that bring together the extraordinary mechanical and pharmacological characteristics of Tecres spacers and the efficacy of the Vancomycin-Gentamicin combination. They are indicated for temporary artificial joint replacement when prosthetic joints require removal due to sepsis. The microbiological efficacy of Vancogenx-Space devices can be attributed to the special production process developed by Tecres that increases the device’s porosity without compromising its mechanical performance.(8) This permits antibiotic release that...

Vancogenx-Space Hip Comes in 6 sizes. (3 head sizes with standard stem and 3 head sizes with XL stem). If the stem is unstable and when using Vancogenx Space SURGICAL TECHNIQUE of the neck should be performed using Vancogenx Remove the prostheses joint. Clean the host site by aggressive debridment removing all residues of cement, if present. File the acetabulum to obtain the ideal shape. Identify the size required using the trial device. Insert the stem into the diaphyseal canal. Vancogenx-Space Knee Comes in 3 sizes. Requires component cementing using Vancogenx cement. SURGICAL TECHNIQUE Clean...

Ordering information SPACER for HIP Spacer with vanco-genta Spacer with genta Head size (mm) Vancogenxspace hip Spacer G Flat Stem Spacer Flat Stem (three-size set) Spacer Flat Stem XL (three-size set) SPACER for KNEE Tibial dimension (mm) Spacer with vanco-genta Spacer with genta Vancogenxspace Knee Spacer for knee (three-size set) Spacer for knee XL (one size)

2. Watanakunakorn C, Tisone JC. Synergism between vancomycin and gentamicin or tobramycin for methicillin-susceptible and methicillin-resistant Staphylococcus aureus strains. Antimicrob Agents Chemother. 1982 Nov;22(5):903-5. 3. E. Bertazzoni Minelli, T. Della Bora, A. Benini Different microbial biofilm formation on polymethylmethacrylate (PMMA) bone cement loaded with gentamicin and vancomycin Anaerobe. 2011 Dec; 17(6): 380-3 4. Trampuz A, Zimmerli W. Prosthetic joint infections: update in diagnosis and treatment. Swiss Med Wkly. 2005 Apr 30;135(17-18):243-51. Review. 5. Penner MJ, Masri BA,...