AQPlaque Analysis Suite Enhanced Plaque Visualization and Evaluation Improved Vascular & Cardiac Plaque Visualization & Evaluation AQPlaque offers a suite of tools for the evaluation and visualization of atherosclerotic plaque. Parameters relating to plaque constitution and morphology, including the overall extent of wall remodeling, luminal encroachment, and the density/intensity distribution of CT/MR values within the plaque, can be characterized with the AQPlaque tools. Reported Clinical Evaluations of AQPlaque In a case study performed by C. Herzog et. al. at the Johann Wolfgang Goethe-University, Frankfurt (Clinical Case Studies in the Third Dimension, Volume 2, 2006, TeraRecon, Inc.), investigators reported a comparison between MDCT, MR, and histopathology for the detection and characterization of atherosclerotic lesions, using the AQPlaque suite. The results suggested that MDCT is superior to MR for detection of such lesions, while MR is superior to MDCT for further sub-characterization of lesion type. The case study reported excellent agreement between observers applying the software tools. AQPlaque Features • AQPlaque tools are integrated with luminal analysis tools for stenosis calculations. • Identify and quantify various tissue types from CT and MR images. • Delineate vessels' outer and inner walls from surrounding tissue and lumen. • Calculate diameters, areas, and percentage of stenosis. • Export images to DICOM, CD, or to a local PC.

AQPlaque Analysis Suite Enhanced Plaque Visualization and Evaluation Aquarius w o r k s t a t i o n • AQPlaque tools are integrated into the optional Vascular Analysis package of the Aquarius Workstation. • For CT images, a set of HU intensity ranges can be defined and mapped to a color overlay to visualize various elements of a lesion. • Flexible region-of-interest tools are available to exclude non-vascular structures. • The volume of each defined tissue category is automatically calculated within the region of interest. • Stenosis measurement may be based on three-point QCA or simple-ratio...