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CONFIDENCE in Trace Analysis of Contaminants using IC-MS Solutions

CONFIDENCE in Trace Analysis of Contaminants using IC-MS Solutions
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CONFIDENCE in Trace Analysis of Contaminants using IC-MS Solutions - 1

more capabilities. new possibilities. Thermo Scientiﬁc + Dionex CONFIDENCE in Trace Analysis of Contaminants using IC-MS Solutions Trace analysis for environmental samples is especially challenging since it requires sensitive detection but also removal of matrix interferences. Ion exchange chromatography coupled with mass detection is an ideal solution for many critical contaminants. The speciﬁcity and selectivity of ion exchange has a greater resolving power for ionic contaminants than reversed phase separations. Dionex ICS-2100 RFIC System Thermo Scientific MSQ Plus Mass Detector • Superior ESI design for low mass ions • Integrated design • High analytical specificity • Rapid screen and target compound analysis • U.S. EPA methods specify IC-MS • High stability and minimal drift • High sensitivity due to specially enhanced transmission efficiency for low mass ions Did you know? When you buy a product from Thermo Fisher Scientiﬁc, you gain the peace of mind that comes from being backed by the largest team of highly qualiﬁed service experts committed to your long-term success. We provide a complete portfolio of services and management solutions designed to help you improve productivity and reduce total cost throughout your equipment lifecycle. In addition to services related to a single instrument, we offer programs to service and maintain multiple instruments, regardless of manufacturer, that will deliver signiﬁcant cost savings. Let our expertise complement yours. Ion Chromatography (IC) and Reagent Free IC (RFIC) were developed primarily for the separation of anions and cations through ion exchange based separations using conductivity detection. Conversely, Mass Spectrometry (MS) methods have been developed for the analysis of organic compounds using reversed phase separations that provide simultaneous mass accuracy and conﬁrmation. The resolving power of reversed phase separations of ionic or mixed mode species is limited given that it does not take advantage of anion- or cation exchange selectivities. Additionally, high ionic strength matrices also cause signiﬁcant signal suppression in the mass detector. A strategy often applied is the use of ion pairing agents and ionic compounds containing a hydrocarbon chain that imparts a certain hydrophobicity forcing ion pair retention on a reversed-phase column. However, ion pairing agents are typically strong acids, w

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CONFIDENCE in Trace Analysis of Contaminants using IC-MS Solutions - 2

ESI source within the MS detector or causing signal suppression. For these reasons, the coupling of ion exchange with MS detection has been problematic in the past. Fortunately, there is an IC-MS solution to overcome many of these separation and detection challenges. By deploying RFIC with high capacity anion exchange separation, you gain premier technology for ease-of-use, improved gradient separations and low level detection. The wide range of Dionex IonPac column choices increase your capacity and selectivity to resolve trace analytes in very EPA Method 332.0 for Perchlorate by IC-MS...

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