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Thermo Scientific
Ion S5 and Ion S5 XL Systems

Ion S5 and Ion S5 XL Systems

Product catalog summary

Overview: The Ion S5 and Ion S5 XL Systems are designed for targeted sequencing applications, offering a simple, scalable, and rapid workflow suitable for panels, microbes, exomes, and transcriptomes. These systems support various chip types, each providing different read capacities and outputs.

Specifications:

Chip Options: Ion 510, 520, 530, and 540 Chips, with read capacities ranging from 2-80 million reads and outputs from 0.3-15 Gb depending on the chip and read length.
Run and Analysis Times: Run times are consistent at 2.5 hours for 200 bp and 4 hours for 400 bp reads. Analysis times vary from 0.5 to 17.5 hours based on chip and read length.
Long-Read Sequencing: Available for research applications like HLA typing, with specific chips supporting up to 12 million reads and outputs up to 4.5 Gb.

System Requirements:

Environment: Operates at 20–30°C with 40–60% humidity, up to 2,000 m altitude.
Power and Dimensions: Requires 100–240 V, 14.5 A, with dimensions of 54.2 cm width, 80.6 cm depth, and 50.9 cm height.

Data Analysis: Utilizes Torrent Suite Software for primary data analysis and Ion Reporter Software for secondary analysis. Supports FASTQ, SFF, BAM, and VCF data formats.

Ion S5 XL System: Includes a Torrent Server with a minimum of 128 GB memory, NVIDIA K40 GPU, and 28 TB storage, running on Ubuntu OS.

Ordering Information: Systems and accessories are available under specific catalog numbers, with enrichment automation options like the Ion Chef and Ion OneTouch 2 Systems.

Note: These systems are for research use only and not for diagnostic procedures.

Catalog excerpts

SPECIFICATION SHEET Ion S5 and Ion S5 XL Systems Targeted sequencing has never been simpler Simple, scalable, and rapid workﬂow for panels, microbes, exomes, and transcriptomes Run time Analysis time** Long-read sequencing for research applications such as human leukocyte antigen (HLA) typing or metagenomic analysis Analysis time** * Expected output with >99% aligned/measured accuracy. Output dependent on read length and application. ** Analysis time to aligned BAM ﬁles. † Ion 510 Chip is only compatible with the Ion Chef ™ System workﬂow for template preparation. The Ion 510

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Target selection solutions Ion AmpliSeq™ technology Library solutions Ion AmpliSeq™ Library Kit Ion Xpress™ Plus Fragment Library Kit Ion Total RNA-Seq Kit v2 Ion Library Equalizer™ Kit 384 barcodes supported by Torrent Suite™ Software Data analysis solutions Torrent Suite Software for primary data analysis Ion Reporter™ Software for secondary data analysis, annotation, ﬁltering, and reporting Ion S5 System speciﬁcations Working environment Temperature: 20–30°C (68–86°F) Humidity: 40–60%, noncondensing Altitude: Up to 2,000 m (6500 ft.) above sea level Thermal output at typical power draw of...

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