Targeted sequencing has never been simpler Ion Torrent™ technology has been referenced in over 1,500 publications in just the first 4 years since its introduction. Now you can drive your research forward using this highly cited technology with the latest innovation in leadingedge benchtop next-generation sequencing: the Ion S5™ and Ion S5™ XL Systems. Whether it’s the Ion S5 System for small-scale studies and lower weekly throughput or the Ion S5 XL System for faster analysis and higher weekly throughput, you’ve got a simple and scalable sequencer that can match your unique project needs. • Less than 15 minutes of sequencer hands-on time. • ess than 45 minutes of hands-on time for a DNA-to-data L targeted sequencing workflow. • ingle sequencer, multiple applications and multiple S chip formats to match dynamic research needs. Cancer research • Identify fusion transcripts in tissue samples. • xplore SNPs, indels, CNVs and even gene expression E levels from 10ng of FFPE DNA or RNA. Speed • 2.5 to 4 hours for a sequencing run. Inherited disease research • Investigate known variants associated with drug metabolism. • As little as 24 hours to go from DNA to data. • Sequence both small and large gene research panels. • iscover SNPs, indels and CNVs for research of rare D or unknown disorders by whole exome sequencing. Small sample input • 0ng low-quality DNA or RNA needed to generate 1 mutational or gene expression profiles. † Automated analysis time includes aligned BAM files. Infectious disease research • Identify and type microbes through genome sequencing. • Assess known variants associated with antibiotic resistance. Aneuploidy research • High–throug

Simple, rapid workflow with less than 45 minutes of hands-on time The combination of Ion AmpliSeq™ technology for target selection, the Ion Chef™ System for automated library and template preparation, and Ion Reporter™ Software for automated variant annotation has made targeted sequencing simpler than ever. Construct library Prepare template Analyze data Hands-on time: 15 minutes Run time: 7 hours Hands-on time: 15 minutes Run time: 11 hours (overnight run) Hands-on/setup time: <15 minutes Run time: 2.5 hours Hands-on time: N/A Run time: 5 hours Ion AmpliSeq™ Cancer Hotspot Panel v2 on the Ion...