ISQ Series Mass Spectrometers Hardware Manual 1R120555-0002 Revision E April 2014

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C Contents Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xiii About Your System. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xiii Related Documentation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xiv System Requirements . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xiv Safety and Special Notices . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .xiv Special Notices...

Maintaining the Calibration Gas Module . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 67 Refilling the Calibrant Reservoir . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 68 Replacing a Dual Filament . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 70 Replacing the Electron Multiplier . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 76 Cleaning Durable Components . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 83 Cleaning Delicate Components. . . . . . . . . . . . . . . . . . . . . . ....

Investigating RF/DC Issues . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112 RF dip is incorrect. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112 RF/DC System Check diagnostic fails. . . . . . . . . . . . . . . . . . . . . . . . . . . . . 112 Investigating Sensitivity Issues . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 113 Poor sensitivity or sudden loss in sensitivity. . . . . . . . . . . . . . . . . . . . . . . . . 114 Poor high mass response. . . . . . . . . . . . . . . . . . . . . . . ....

Replacing Components of the Manifold . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 208 Manifold Door Hinge . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 209 Front Manifold Plate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 214 Back Manifold Plate . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 220 Tray Alignment Pins, Magnet Yoke, Source Insertion Guide, Source Magnets and Front Manifold O-ring . . . . . . . . . . . . . . . . . . . . . . . . . . . . 223 Vent Valve Knob and...

Replacing the Calibration Gas Components . . . . . . . . . . . . . . . . . . . . . . . . . . 334 Calibration Gas Module . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 335 Calibrant Reservoir Kit . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 344 Gas Mixing Chamber . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 345 Transfer Line . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 346 Replacing Fans and Filters . . . . . . . . . . . . . . . . . . . . . ....

Declaration Manufacturer: Thermo Fisher Scientific Thermo Fisher Scientific is the manufacturer of the instrument described in this manual and, as such, is responsible for the instrument safety, reliability and performance only if: • installation • re-calibration • changes and repairs have been carried out by authorized personnel and if: • the local installation complies with local law regulations • the instrument is used according to the instructions provided and if its operation is only entrusted to qualified trained personnel Thermo Fisher Scientific is not liable for any damages derived from...

Low Voltage Safety Compliance This device complies with Low Voltage Directive 2006/95/EC and harmonized standard EN 61010-1:2001. FCC Compliance Statement THIS DEVICE COMPLIES WITH PART 15 OF THE FCC RULES. OPERATION IS SUBJECT TO THE FOLLOWING TWO CONDITIONS: (1) THIS DEVICE MAY NOT CAUSE HARMFUL INTERFERENCE, AND (2) THIS DEVICE MUST ACCEPT ANY INTERFERENCE RECEIVED, INCLUDING INTERFERENCE THAT MAY CAUSE UNDESIRED OPERATION. CAUTION Read and understand the various precautionary notes, signs, and symbols contained inside this manual pertaining to the safe use and operation of this product before...

For manufacturing location, see the label on the instrument WEEE Compliance This product is required to comply with the European Union’s Waste Electrical & Electronic Equipment (WEEE) Directive 2002/96/EC. It is marked with the following symbol: Thermo Fisher Scientific has contracted with one or more recycling or disposal companies in each European Union (EU) Member State, and these companies should dispose of or recycle this product. See www.thermoscientific.com/ rohsweee for further information on Thermo Fisher Scientific’s compliance with these Directives and the recyclers in your country....

Conformité DEEE Ce produit doit être conforme à la directive européenne (2002/96/EC) des Déchets d'Equipements Electriques et Electroniques (DEEE). Il est marqué par le symbole suivant: Thermo Fisher Scientific s'est associé avec une ou plusieurs compagnies de recyclage dans chaque état membre de l’union européenne et ce produit devrait être collecté ou recyclé par celles-ci. Davantage d'informations sur la conformité de Thermo Fisher Scientific à ces directives, les recycleurs dans votre pays et les informations sur les produits Thermo Fisher Scientific qui peuvent aider la détection des substances...