PRODUCT SPECIFICATIONS The Thermo Scientific™ LTQ XL™ linear ion trap mass spectrometer Everyday affordability with MSn Keywords LTQ XL linear ion trap mass spectrometer, MSn (CRM) capabilities, proteomics, metabolite identification, forensic analysis, clinical research, teaching The LTQ XL linear ion trap mass spectrometer delivers high sensitivity full scan MS along with in-depth MSn (CRM) capabilities. If you are in the market for an extremely affordable general-purpose mass spectrometer, look no further than the LTQ XL. Applications include proteomics, metabolite identification, forensic analysis, clinical research and teaching. General purpose utility extends to users in academia, industry and government alike. Now includes updated software with Windows 10 compatibility enabling full support today and into the future A single quadrupole offers no more than Selected Ion Monitoring (SIM). A triple quadrupole adds Selected Reaction Monitoring (SRM) where a selected ion can be fragmented into a product ion. A linear ion trap goes further by enabling Consecutive Reaction Monitoring (CRM) where a selected ion is fragmented into a product ion and the resulting product ion further fragmented in additional consecutive steps (MS n). Each additional fragmentation step makes compound identification more certain and facilitates structural characterization. Selected Ion (MS1) First Fragmentation Second Fragmentation

Powerful tools for structural characterization Collision Induced Dissociation (CID) • Resonance excitation of precursor at low q; low energy collisions with He • Universal, no tuning required, high efficiency Pulsed “q” Dissociation (PQD) • Short resonant excitation of precursor at high q, rapid shift to very low q, high energy collisions with He • Selective, no low mass cutoff, low noise • Tuning required, low efficiency Hardware features Thermo Scientific™ Ion Max™ API source • With ESI, HESI, APCI and APPI options • Sweep gas reduces chemical noise • 60° interchangeable ion probe orientation...

Data system features Hardware • High performance PC • 27 inch LED Monitor with 1920 x 1080 resolution Operating system • Microsoft Windows© 10 x 64 enterprise IoT LTSB 2016 Thermo Scientific™ software • LTQ Instrument Control Software • Thermo Scientific™ Xcalibur™ software for method setup, data acquisition, data processing, and reporting • Thermo Scientific™ FreeStyle™ software to view and analyze data Scan functions • Predictive Automatic Gain Control (AGC) delivers up to 10 Hz data dependent MS/MS acquisition • Full-scan mass spectra for sensitive analyses and rapid screening of unknown compounds...

Gas • One high-purity (99% pure, flow rate 15 L/min) nitrogen gas supply for the API source Performance specifications Mass range • m/z 15–200 • One ultra high-purity helium gas supply (99.998% pure) with less than 1 ppm each of water, oxygen, and total hydrocarbons for the mass analyzer Environment • System averages 2300 W (8000 Btu/h) output when considering air conditioning needs Linear dynamic range • Under typical experimental conditions, at least four and a half (4.5) orders of magnitude • Operating environment must be 15–27 °C (59–80 °F) and relative humidity must be 40–80% with no condensation...