Thermo Scientific TSQ Quantiva Triple-Stage Quadrupole Mass Spectrometer Extreme quantitative performance with unprecedented ease

Unsurpassed quantitation Continual changes in research and regulatory requirements drive the need for ever-lower limits of detection and quantitation. A modern triple quadrupole LC-MS system must be capable of attaining the lowest LODs and LOQs run after run and day after day, regardless of sample type or matrix. The Thermo Scientific™ TSQ Quantiva™ triple-stage quadrupole mass spectrometer uses active ion management to exceed even the most stringent analytical requirements with superb sensitivity, speed, and dynamic range. It does so with an ease of operation—from method development through...

Sensitive, robust peptide quantitation Putative biomarkers and other proteins of scientific interest are frequently obscured by common high-abundance proteins. The TSQ Quantiva MS and Thermo Scientific™ EASY-Spray NG™ ion source supply the sensitivity, precision, and dynamic range needed to screen for and validate such elusive targets. Thermo Scientific™ Pinpoint™ software leverages previously acquired discovery data to vastly simplify development Total solutions for clinical research and forensic toxicology Industry-leading sensitivity for environmental and food testing The cutting edge of clinical...

AIM technology delivers extreme sensitivity and excellent robustness When the goal is maximum possible sensitivity, speed, and robustness in a triple quadrupole mass spectrometer, every aspect of design must be examined. Every lens transition, every fringing field, and every mechanical and electrical tolerance must be considered and optimized in concert. The result of this exercise is Thermo Scientific™ Active Ion Management (AIM™) technology. AIM technology maximizes ion transmission, eliminates major sources of noise, and precisely isolates analytes to achieve extreme quantitative performance....

Ultrafast scanning The axial DC field applied to the active collision cell speeds ion transits, yielding ultrafast SRM scanning with zero cross talk. High-capacity transfer tube Superior selectivity HyperQuad quadrupole mass filters with asymmetric RF drive increase ion transmission and SRM sensitivity, and provide industry-leading high-resolution 0.2 FWHM selected-reaction monitoring (HSRM). Reduced noise Curved ion beam guide stops neutrals and high-velocity clusters with a neutral blocker, keeping the ion optics cleaner, reducing noise, and increasing sensitivity. Greater sensitivity and dynamic...

Simplified, integrated software delivers performance with ease Integral to the TSQ Quantiva system is entirely new software for method development and instrument operation; software that ensures more performance with less effort. The drag-and-drop method editor simplifies method development and does away with cumbersome tune files. Close integration with workflow-specific software packages ensures seamless, effective operation for even the most challenging applications. TSQ Quantiva software helps researchers focus on their science instead of their instruments. 250 pesticides in onion matrix...

Pinpoint Software Pinpoint software leverages previously acquired discovery data, and the commonality between MS platforms, to largely automate the development of intelligent SRM assays for targeted protein quantitation. It also streamlines data acquisition and analysis, and the resulting data can be used to further refine the method. Pharmaceutical Analysis Clinical Research and Forensic Toxicology LCquan Software LCouan software is a 21 CFR Part 11-compliant solution for method development, data review, processing, reporting, and data export in drug discovery and development experiments. It...

Transforming science with the next generation of mass spectrometers The TSQ Quantiva mass spectrometer is just one of a family of transformational, next-generation Thermo Scientific mass spectrometers that combine unprecedented performance and usability. Others include: • Thermo Scientific™ TSQ Endura™ triple-stage quadrupole mass spectrometer • Thermo Scientific™ Orbitrap Fusion™ Tribrid™ mass spectrometer These next-generation instruments are built on a foundation of shared, state-of-the-art hardware and software components. This commonality makes it easier to transfer methods from one instrument...