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Vanquish Horizon UHPLC System

Vanquish Horizon UHPLC System
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Vanquish Horizon UHPLC System

Product catalog summary
Introduction
The Thermo Scientific Vanquish UHPLC System is designed to enhance chromatographic performance with advanced technology and user-friendly features, providing efficient solutions to scientific challenges.
System Overview
The Vanquish UHPLC System is a biocompatible, integrated system offering high power, accuracy, and sensitivity. It supports up to 1500 bar pressure, precise flow and gradient control, and can handle up to 8832 samples with automated workflows.
Performance and Throughput
Engineered for high resolution and throughput, the system is driven by the Thermo Scientific Dionex Chromeleon Chromatography Data System (CDS), allowing for high sample capacity and efficient analysis.
Key Features
  • Separation Power: Supports high backpressures and advanced column technologies.
  • Sample Handling: Offers precise injections and large sample capacity with automated barcode reading.
  • Temperature Control: Features active pre-heating and multiple thermostatting modes.
  • Detection Sensitivity: Utilizes LightPipe technology for low noise levels and high sensitivity detection.
Technological Innovations
Incorporates SmartFlow pumping technology for precise flow control and low pulsation, with Viper fingertight fittings for reliable connections and optimized fluidics for minimal dispersion.
Software Integration
Controlled by Chromeleon CDS, the system offers operational simplicity, smart start-up and shutdown, and comprehensive audit trails, supporting live data monitoring and secure data management.
Mass Spectrometry Compatibility
The system can integrate with Thermo Scientific mass spectrometers, enhancing analytical capabilities and providing detailed compound identification.
Conclusion
The Vanquish UHPLC System is a powerful tool for chromatographers, offering enhanced performance, ease of use, and integration with advanced technologies for modern scientific research.
Mass Spectrometry Integration
The document discusses the advantages of using mass spectrometers, particularly in quantitation workflows with selected reaction monitoring (SRM) analyses, and highlights integration with Thermo Scientific's Orbitrap technologies for high-resolution, accurate mass detection by LC-MS.
Key Technologies
Mentions the Thermo Scientific™ Exactive™ line of benchtop mass spectrometers and the Thermo Scientific™ Orbitrap Fusion™ Tribrid™ mass spectrometer, emphasizing their benefits in high-resolution mass detection.
Data Analysis
Presents a full scan LC-MS analysis of Omeprazole and its metabolites in human urine using the Vanquish UHPLC and Q Exactive Plus LC-MS system, with graphical data showing relative abundance against retention time and m/z values.
Contact Information
Provides contact details for Thermo Fisher Scientific's offices across various regions, including Europe, Asia, and the Americas.
Additional Resources
Includes a link and QR code for accessing a virtual demo of the system, along with videos and other resources.
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Catalog excerpts

Vanquish Horizon UHPLC System-1

Thermo Scientific Vanquish UHPLC System Revolutionize Your UHPLC Experience

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Vanquish Horizon UHPLC System-2

We feel that achieving better performance is not the same as spending more effort. We know that every breakthrough starts with a challenge. We want that challenge to be your science, not your instrument. Our mission is to let you find better answers, more answers, and get them faster. Make your life as a chromatographer easier by seeing what you couldn’t see before and doing what you couldn’t do before. In 2010 we embraced UHPLC as the standard for all our liquid chromatography systems. Now we offer the Thermo Scientific™ Vanquish™ UHPLC system, combining all our knowledge and passion for chromatography...

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Vanquish Horizon UHPLC System-3

What is the Vanquish UHPLC System? The Vanquish system was built around the column and the user to deliver better separations, more results, and easier interaction. The Vanquish UHPLC system is an integrated, fully biocompatible system, addressing the needs of chromatographers performing state-of-the-art UHPLC. The Vanquish system can … … drive the separation with more power • 1500 bar (22,000 psi) of pump pressure at flow rates up to 5 mL/min • Industry-leading flow and gradient precision • 2 x 3 solvent channels … handle the sample with more accuracy • Up to 23 well plates for 8832 samples...

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Vanquish Horizon UHPLC System-4

You have a method with a cycle time of 60 s You need to analyze 8000 samples One weekend full of results The Vanquish system can hold up to 23 x 384 samples The Vanquish system takes high-end UHPLC to a new level, offering more resolution while meeting the throughput demands of modern laboratories. The system is driven by the goldstandard Thermo Scientific™ Dionex™ Chromeleon™ Chromatography Data System (CDS) software and delivers better separations, more results and easier interaction. The Vanquish system delivers these values simultaneously, without compromise. When combined with the Thermo...

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Vanquish Horizon UHPLC System-5

There are many different questions in science, and all require a dedicated answer. The Vanquish system helps you to get that answer, every time. Better separations Separate more peaks than ever before. The Vanquish system improves specifications on all fronts. It supports higher backpressures, better thermostatting, optimized volumes, better linearity, and more sensitivity. The Vanquish system supports you without compromising performance while applying the most advanced column technologies, for all of your critical separations. More results Regain time during your projects. The system improves...

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Vanquish Horizon UHPLC System-6

Pressure is only half the story in Ultra High Performance LC. How you can use the available power of 1500 bar is what separates the Vanquish system from the others. Maximize resolution or maximize throughput, both require a system that has more to offer than just high pressure. The Vanquish system was designed to work on both these ends and everywhere in between. Resolution Matters Better Separations Take full benefit from the impressive power of the Vanquish system. Run your analysis on long UHPLC columns with ultra high-efficient sub-2 µm particles or by applying column chains for maximum efficiency....

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Vanquish Horizon UHPLC System-7

Throughput Beyond Speed Never Run Out of Sample Reproducibility Counts For throughput, you need more than fast chromatography. All the hardware needs to keep pace with the analysis speed. The Vanquish system injects your sample accurately and precisely with fast cycle times every time you need it. You can run large numbers of samples out of a wide range of sample vials and well plates, perfectly matching your sample volume demands. Count on the reliable bar code identification of the diverse racks and well plates by automated recognition and the accurate Charger module sample loading technology....

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Vanquish Horizon UHPLC System-8

The Vanquish system was developed to offer more pressure capabilities than ever before, without any tradeoff on durability or robustness. From ultra-fast to extremely shallow gradients at pressures up to 1500 bar, the industry-leading fourth generation SmartFlow™ pumping technology of the Vanquish system provides you with unmatched retention time reproducibility and lowest baseline noise for the highest detection sensitivity. 1000 Profit from the perfect harmonization of pumping control and smart fluidics for lowest gradient delays and exceptional gradient profile formation. • Enjoy lowest pulsation...

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Vanquish Horizon UHPLC System-9

Handle the Sample The Vanquish system combines maximum injection precision with huge sample capacity and high-throughput capabilities. • Rely on your results thanks to unsurpassed sample dosage precision The fully biocompatible fluidics is consequently optimized for the highest ruggedness and uptime even under the toughest system pressure and eluent conditions. • Take advantage of maximum sample integrity by an innovative air stream cooling, even in challenging environments • Forget about tedious sample configuration thanks to the automated barcode reader Get more through the Chromeleon CDS driven...

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Vanquish Horizon UHPLC System-10

Temperature rules retention, selectivity and efficiency in chromatography. And the Vanquish system is your key to pave the way to maximum efficiency and resolution through an exceptional temperature control. • Perfectly align eluent and column temperature by our unique active pre-heating concept • Benefit from the unique choice between still air and forced air thermostatting capabilities • Extend your workflow capabilities with up to three independent column chambers and multiple switching valves Ensure best efficiency by keeping the frictional heat within the column — boost your separation speed...

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Vanquish Horizon UHPLC System-11

The LightPipe technology within the Diode Array Detector (DAD) provides you with an unmatched detection experience. It achieves a wide linear range and industry-leading signal-to-noise performance, even beyond the capabilities of variable wavelength detectors. • Benefit from the best sensitivity with low-dispersion 10 mm and 60 mm flow cells and a wide linearity to comply with even the most demanding applications • Acquire simultaneously up to ten signal channels and a spectrum 3D field at 200 Hz • Optimize sensitivity, linearity, and spectral resolution of your application with four programmable...

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