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Yukon Choice PC

Yukon Choice PC

Yukon Choice PC

Product catalog summary
Introduction
The Yukon® Choice PC is a biodegradable polymer drug-eluting stent (DES) system designed to prevent stent thrombosis. It is coated with Sirolimus, polylactide (PLA), and shellac, offering excellent long-term clinical outcomes.

Clinical Trials and Efficacy
In trials such as ISAR-TEST 3 and 4, the Yukon Choice PC demonstrated angiographic and clinical equivalence to the Cypher stent over 1 and 3 years. A meta-analysis involving over 4000 patients showed a significant reduction in Very Late Stent Thrombosis (VLST) with the Yukon Choice PC compared to the Cypher stent.

Design and Features
The stent features a unique microporous surface that enhances drug binding and reduces polymer flaking. It is designed for easy access to lesions with a flexible tip and robust segment. The stent's low profile and homogeneous expansion improve deliverability and radial force.

Technical Specifications
The stent is made from medical stainless steel with a microporous surface. It has a crossing profile of 0.035” and a strut thickness of 0.0034”. The balloon marker is made of platinum/iridium, and the recommended guide wire is 0.014”.

Performance and Safety
Pre-clinical evaluations confirm the safety of the Yukon Choice PC over bare metal stents (BMS) and conventional DES. The microporous surface shows a trend towards reduced binary restenosis rates. The stent releases Sirolimus for up to 4 weeks, maintaining significant tissue concentration.

Ordering Information
The product matrix provides various sizes and lengths for different balloon diameters, with specific article numbers for ordering.

Conclusion
The Yukon Choice PC offers a significant reduction in stent thrombosis risk without compromising efficacy, making it a reliable choice for coronary interventions.
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Catalog excerpts

Yukon Choice PC-1

Sirolimus Eluting Coronary Stent System Translumina – Prevent your Stent Thrombosis

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Yukon Choice PC-2

Yukon® Choice PC Excellent Long-Term Clinical Outcome The Translumina Yukon Choice PC drug-eluting stent, coated with Rapamycin (Sirolimus) and the biodegradable components polylactide and shellac, has an excellent history of pre-clinical and clinical results.[1,2] In two independent trials ISAR-TEST 3 and ISAR-TEST 4 the Yukon Choice PC showed angiographic and clinical equivalence with the Cypher stent after 1 year and 3 years of follow-up.[3,4] Latest clinical data, published by G.Stefanini et al [5], show the excellent long-term outcome of the Yukon Choice PC in a meta-analysis, comparing...

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Yukon Choice PC-3

Pre-Clinical Data [ 1 ] Extensive pre-clinical evaluations prove the safety of Yukon Choice PC over BMS and conventional DES: Sirolimus [ng/mg tissue] Sirolimus release [%] vascular tissue prevascular tissue Yukon Choice PC shows a release of sirolimus up to 4 weeks with a significant tissue concentration in the arterial segments. Yukon Choice PC shows a reduced neointimal formation compared to a bare metal stent without compromising vascular healing. Safety of the BMS Platform [  2  ] The microporous surface of the Yukon Choice PC is well studied for its efficacy and safety when compared to...

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Yukon Choice PC-4

Efficacy [  3,4  ] The ISAR-TEST 4 is the first prospective randomized trial which compares different DES i.e. Yukon Choice PC, Xience and Cypher for their efficacy & safety in over 2600 patients. Target lesion revascularization (%) Target lesion revascularization (%) Xience && Cypher 20,9% Xience Cypher 20,9% Yukon Choice PC 20,1% Yukon Choice PC 20,1% Xience && Cypher 14,2% Xience Cypher 14,2% Yukon Choice PC 13,9% Yukon Choice PC 13,9% Month after randomization Month after randomization Month after randomization Month after randomization The Yukon Choice PC with biodegradable polymer proves...

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Yukon Choice PC-5

Yukon® Choice PC Sirolimus Eluting Coronary Stent System The Biodegradable Polymer DES now with a lot of new features The new distal shaft Our high performance shaft consisting of a new material provides excellent pushability and kink resistance. This feature allows for high manoeuvrability. The new stent delivery system The new flexible tip The new designed luer The transparent luer has a positive, tactile feel assisting in navigation of the system. It is designed with an integrated protection to minimize any kinking. The soft tip material combined with an improved robust segment ensures perfect...

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Yukon Choice PC-6

Sirolimus Eluting Coronary Stent System Yukon® Choice PC Product matrix / Ordering information* Balloon Stent length [mm] & Article number 8 Stent length [mm] & Article number * Please contact our customer service for available sizes Compliance chart Inflation pressure [bar or 10 - 5 Pascal] NP © 013 Translumina GmbH 2 All Rights Reserved ® Yukon, Yukon Choice, Pearl Surface and Translumina are registered trademarks of translumina GmbH Please refer to the Instruction for Use supplied with these devices for indications, contraindications, adverse effects, suggested procedures, warnings and precautions....

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All Translumina catalogs and technical brochures

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.