Yukon®Chrome PC
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Sirolimus Eluting CoCr Coronary Stent System

Yukon® Chrome PC DES coating with excellent long-term clinical outcome The Translumina Yukon drug-eluting stent product family, coated with Rapamycin (Sirolimus) and the biodegradable component polylactide (PLA), has an excellent history of pre-clinical and long-term clinical results.[1-10] The Yukon Chrome PC has the identical coating technique and coating properties (dosage, thick ness) like the clinically proven Yukon Choice PC. In two independent trials ISAR-TEST 3 and ISAR-TEST 4 the Yukon DES platform showed improved longterm performance compared to 1st. Generation DES over a time...

Published Pre-clinical and BMS Data [ 1, 2 ] Sirolimus (ng/mg tissue) Sirolimus release (%) Extensive pre-clinical evaluations prove the safety of the Yukon DES platform over BMS. The microporous surface shows a trend towards a reduced rate of binary restenosis with equivalent safety, which proves that it is safe and feasible to use as a drug reservoir for a DES. vascular tissue perivascular tissue Comparison of smooth (electropolished) stent surface (A) and rough Yukon DES coating shows a release of sirolimus up to 4 weeks (microstructured) stent surface (B). with a significant tissue...

Excellent 5 and 10 year long-term clinical data [ 9, 10 ] The final 10 year long-term clinical follow-up of the ISAR-TEST 4 randomized controlled clinical trial showed excellent safety and efficacy data for the Yukon Choice PC when compared with the Cypher and Xience V stent. The definite and probable stent thrombosis was only 1,8% for the Yukon compared to 2,5% and 3,7% for the 2 permanent polymer coated competitor DES. ARC definite or probable stent thrombosis Definite or probable stent thrombosis (%) Early generation PP-SES New generation PP-EES New generation BP-SES 10 year clinical...

Yukon® Chrome PC Sirolimus Eluting CoCr Coronary Stent System The new high tech Cobalt Chromium Stent System 2-Connector-Design The new design with only 2 connector struts guarantees maximum flexibility and side branch access. A CoCr Stent - designed for all lesions The suitable catheter The luer is designed with an integrated kinking protection. Bifurcation stenting The flexible tip ensures perfect crossability and trackability. With a cell circumference of up to 18,5 mm the Yukon Chrome PC allows perfect side branch access which is essential for bifurcation stenting. Scanning Electron...

Sirolimus Eluting CoCr Coronary Stent System Yukon® Chrome PC Product matrix / Ordering information Small vessel design (SV) Balloon Stent length [mm] & Article number Medium vessel design (MV) Stent length [mm] & Article number Compliance chart Inflation pressure [bar or 105 Pascal] NP 1434 © 020 Translumina GmbH 2 All Rights Reserved ®Yukon, Yukon Choice, Yukon Chrome, PEARL Surface Art.Nr. MK 0058/REV4 and Translumina are registered trademarks of translumina GmbH Please refer to the Instruction for Use supplied with these devices for indications, contraindications, adverse effects,...