Combined Oscillatory PEP and nebulizer treatments reduce overall therapy time which may improve compliance 100 Total Emitted Mass (%) ‡ One device for all patient groups Resistance is not position dependent so patients can hold the device in the most natural position Aerobika* Oscillating PEP with Nebulizer Nebulizer alone 177±21 μg Acapella† Oscillating PEP with Nebulizer Combine with the AEROECLIPSE* XL BAN and Ombra* Compressor Part Number Description Aerobika* Oscillating Positive Expiratory Pressure Therapy System Case Size (includes Oscillating PEP device with mouthpiece and Instructions for Use) EN, FR, ES, DE, NL, IT, SV, DA, EL, TR, PL, PT, ZH, AR Effective aerosol delivery for combined nebulizer treatments Durable design is easy to clean/disinfect and is dishwasher safe Contact Information: Canadian Hospital Distribution: Authorised European Representative: Trudell Medical International 725 Third Street, London, Ontario, Canada, N5V 5G4 Phone: +1-519-455-7060 Fax: +1-519-455-7858 [email protected] www.trudellmed.com Trudell Medical Marketing Limited 758 Third Street, London, Ontario, Canada N5V 5J7 [email protected] www.tmml.com Trudell Medical International Europe Ltd. BioCity Nottingham, Pennyfoot Street Nottingham, NG1 1GF, UK [email protected] www.aerobikaopep.com 1 McCool FD, Rosen MJ. Nonpharmacologic Airway Clearance Therapies: ACCP Evidence-Based Clinical Practice Guidelines. Chest 2006;129(1):250S-259S. 2 S Svenningsen, M Kirby, J Suggett, A Wheatley, N Kanhere, A Hasany, S Blamires, G Parraga and DG McCormack. Oscillatory Positive Expiratory Pressure in Chronic Obstructive Pulmonary Disease. Abstract submitted for publication. 3 Marks HJ. Airway Clearance Devices in Cystic Fibrosis. Paediatric Respiratory Reviews 2007;8:17-23. 4 Marks JH. Airway Clearance Devices in Cystic Fibrosis. Paediatric Respiratory Reviews 2007;8:17-23. ‡ TMI Aerosol Lab, Data on File: 4.0 mL Ipratropium bromide @ 15 L/min ± 5%; continuous delivery with an AEROECLIPSE* II Breath Actuated Nebulizer (BAN). 110019-001 Rev A. * trade marks and registered trade marks of Trudell Medical International. † trade marks of the respective company. Copyright © Trudell Medical International 2013. All rights reserved. Oscillating Positive Expiratory Pressure Therapy System

Time (seconds) accommodates small volume nebulizers Low-resistance valve -' exhalation without removing from mouth SIMPLICITY AND PERFORMANCE IN ONE DEVICE Oscillating Positive • Oscillations create short bursts of increased expiratory resistance to thin, dislodge and move mucus to the upper airways where it can be coughed out • Oscillations start at the beginning of each exhalation and continue through • Aids in lung hygiene and helps prevent • Improves gas transfer and lowers air design fits comfortably Designed to ensure correct assembly every time patient's capacity Airway Clearance for Chronic...