Inhalation Systems for preclinical research
17Pages

{{requestButtons}}

Catalog excerpts

Inhalation Systems for preclinical research - 1

Sophisticated Life Science Research Instrumentation Inhalation Complete Toxicology Systems

Open the catalog to page 1
Inhalation Systems for preclinical research - 2

Modular Inhalation Systems Complete Solutions for Inhalation Studies ■ Modular Inhalation Systems ■ Head Nose Only Exposure Units ■ Head Snout Only Exposure Units ■ Whole Body Exposure Units ■ Aerosol Conditioning Units ■ Liquid Aerosol and Vapor Generators ■ Aerosol Generators for Special Applications ■ Cigarette Smoke Generators ■ Offline Aerosol Analysis ■ Real-Time Aerosol Analysis ■ Cell Culture Exposure System Whole Body Unit with a volume of approx. 0.95 m3 TSE Systems develops and produces state-of-the-art exposure systems by the continual further development of the systems and...

Open the catalog to page 2
Inhalation Systems for preclinical research - 3

Modular Exposure Systems According to the system requirements, the modular design permits working with liquid and dust aerosols, vapors and special applications such as metered dosed inhalers. Special exposure systems for administering cigarette smoke are available. Aerosol nozzle Aerosol conditioning unit The exposure units are available for animals from mouse to dog sizes as standard versions; for larger animals according to the user’s specifications. Small or larger numbers of animals can be used; this depends on the system design and size. Tests can be carried out with a slight vacuum...

Open the catalog to page 3
Inhalation Systems for preclinical research - 4

Head Nose Only Exposure Units A Head Nose Only Unit with one segment Head Nose Only Units are characterized by: administration of the test substance via the nose – in particular, reduced skin and fur contamination ■  Low sample consumption – particularly advisable for highly toxic or expensive test substances or when the test substance is in short supply ■  Usability for short-term exposure tests with rapid achievement of the equilibrium concentration and by rapid flooding with fresh air at the end of the exposure Head Nose Only Unit with aerosol conditioning units Overview The modular...

Open the catalog to page 4
Inhalation Systems for preclinical research - 5

A view into the open Head Nose Only Unit from above Schematic diagram showing the directed-flow design Technical Design Animal cages made of glass or plastic for rodents The Head Nose Only Units have a directed-flow design, i.e. there is no rebreathing of expired air. The test atmosphere flows into an inner plenum that directs the flow towards the nose or head of each test animal. The exhaled air is then discarded along with the excess air flow into an outer plenum. The validation of the equilibrium distribution and directed-flow design was carried out in 1994 and 2007 by Prof. Pauluhn....

Open the catalog to page 5
Inhalation Systems for preclinical research - 6

Head Snout Only Exposure Units Upper unit with dust generator Upper unit connections A Dog Exposure Unit for the application of liquid aerosols with inhalation mask, holding device and leather harness for the dog Dog Exposure Unit with ultrasonic nebulizer Dog Exposure Unit with dog inhalation mask in front Exposure Units for Dogs Special system solutions are Head Nose Only Units for dogs – aerosol administration is possible by using face masks of different sizes. The units can be adapted for the application of liquid and dust aerosols as well as vapors – according to customerspecific...

Open the catalog to page 6
Inhalation Systems for preclinical research - 7

Whole Body Exposure Units Whole Body Unit – standard version Whole Body Unit for small laboratories Whole Body Units with aerosol conditioning and exhaust air line – in the background a mounting panel with flow control units Spacious Exposure Units standard sizes of stainless steel cages types of cage carrier racks are available for the highest degree of flexibility Discharge stopcock for detergent solution disposal at the lowest point of chamber Whole Body Units allow the simulation of real exposure conditions for a wide range and a large number of animals. Many sizes are available as...

Open the catalog to page 7
Inhalation Systems for preclinical research - 8

Temperature and humidity sensor in Head Nose Only Unit Side view showing various connections Design and specifications of the sensors are adapted for use with the particular inhalation system. The measured values convince because of their high degree of accuracy and reproducibility. Electronic data acquisition of the sensors takes place via stateof-the-art interfaces with automatic transmission and storage of the measurement data. Special sensor holders and ports are provided according to the particular version of the inhalation system. Inner view of a small Whole Body Unit Sensor types:...

Open the catalog to page 8
Inhalation Systems for preclinical research - 9

Aerosol Conditioning Units Aerosol conditioning line for Whole Body Unit Water-jacketed mixing units for aerosol conditioning Small Whole Body Unit with aerosol conditioning line TSE Systems provides different kinds of aerosol conditioning units according to the aerosol properties and the individual customer’s requirements. ■  Dual Aerosol-air mixing device with CO sensor Humidity conditioning line preseparation of large and small aerosol particles via preseparator and cyclone Collection of aerosol remaining in the preseparator unit for reuse or controlled disposal Different types of...

Open the catalog to page 9
Inhalation Systems for preclinical research - 10

Liquid Aerosol and Vapor Generators Aerosol nozzle Vapor generator for volatile organic compounds (VOCs) Aerosol nozzle outlet area – Ultrasonic nebulizer Aerosol Nozzles Various aerosol nozzles are provided for the efficient nebulization of liquids in air and to generate aerosols with different particle sizes, e.g. two-stream nozzles with different specifications. An essential feature of the nozzles is a very uniform cone-shaped cloud of test substance and very small droplet sizes. Aerosol nozzle – mounted on preseparator As well as the generation of liquid aerosols via an aerosol nozzle,...

Open the catalog to page 10
Inhalation Systems for preclinical research - 11

Aerosol Generators for Special Applications Dust Generators Dust Generator acc. to Wright Mixing unit of the MDI Activator-16 MDI Activators and Others As a special solution in the aerosol generation field TSE Systems offers activators for the automatically controlled triggering of MDIs – single-place and multi-place solutions are available. Our MDI Activator-16 allows the individual and computer-controlled operation of 16 metered dose inhalers at the same time. The main advantage of an MDI application is the use of test substances consisting of the same compounds or generated under similar...

Open the catalog to page 11

All TSE Systems catalogs and technical brochures

  1. IntelliCage

    12 Pages

  2. MotoRater

    3 Pages

  3. PhenoMaster

    13 Pages