Multi-Conditioning System

Product catalog summary

Overview
The TSE Multi Conditioning System (MCS) is a versatile research platform designed for studying learning, memory, emotion, and stress-related behaviors in mice and rats. It supports nine different paradigms within a single system, offering flexibility and efficiency for researchers.

Hardware Specifications
The system includes a universal base unit available for both rats and mice or mice only. It features sound attenuating housing, a sliding floor for easy arena changes, and software-controlled lighting and acoustic signals. The infrared light beam frame allows for high-resolution movement detection.

Modular Arenas and Accessories
Arenas come in various sizes and designs, compatible with shock grids and other accessories. The system supports simultaneous video monitoring and integration with additional equipment like microphones and telemetry systems.

Software Packages
The MCS offers three software packages tailored to different behavioral paradigms:

Package 1 - Fear Conditioning: Suitable for Alzheimer's and anxiety research, featuring comprehensive freezing and movement analysis.
Package 2 - Two-Compartment Paradigms: Includes paradigms like Active/Passive Avoidance and Light/Dark Test, applicable for depression and addiction studies.
Package 3 - Locomotor Activity/Open Field: Assesses exploratory behavior and anxiety, with extensive parameter calculations and graphical display options.

Advantages
The system is cost-effective, space-saving, and flexible, supporting various animal models and testing conditions. It ensures comparability across paradigms with common hardware and software.

Service and Warranty
TSE Systems provides a two-year ALL-IN Premium Warranty, including technical support and maintenance options post-warranty.

Selected Publications
The document lists several studies utilizing the MCS in research areas such as immunology, OCD, anxiety, PTSD, Alzheimer's, and depression, highlighting its application in diverse scientific investigations.

Catalog excerpts

Sophisticated Life Science Research Instrumentation Multi Conditioning The ALL-IN-ONE Solution for Mice & Rats Active Avoidance Latent Inhibition Learned Helplessness Place Preference Passive Avoidance Light/Dark Test Fear Conditioning Panic Response Open Field

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Multi Conditioning: Dedicated Software Depending on the behavioral paradigm you choose, the Multi Conditioning System offers three distinct software packages that can be purchased in any combination. Each of these software packages features a user-friendly interface with a highly flexible trial parameter selection window which guides the user step-by-step through experimental design. The software can control up to four test boxes simultaneously. Additionally, basic GLP functions such as user administration and the creation of an audit trail are included as well. Stimulus elements Flexible camera...

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Selected Publications Sophisticated Life Science Research Instrumentation Fear Conditioning in Immunology Research Osborne BF, Caulfield JI, Solomotis SA, Schwarz JM. Neonatal infection produces significant changes in immune function with no associated learning deficits in juvenile rats. Dev Neurobiol. 2017 Oct;77(10):1221-1236. Active Avoidance Task in OCD Research Hatalova H, Radostova D, Pistikova A, Vales K, Stuchlik A. Detrimental effect of clomipramine on hippocampus-dependent learning in an animal model of obsessivecompulsive disorder induced by sensitization with d2/d3 agonist quinpirole....

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*Prices are pre-tax. They exclude delivery charges and customs duties and do not include additional charges for installation or activation options. Prices are indicative only and may vary by country, with changes to the cost of raw materials and exchange rates.

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