TGR Thermal Gradient Ring General The TGR is a novel device for THERMAL PREFERENCE PHENOTYPING in mice, ac-cording to the method devised by Dr. Katharina Zimmermann. THERMAL PREFERENCE PHENOTYPING IN MICE ACCODING TO ZIMMERMANN’S METHOD Main Features l New circular design, ID 45cm, OD 57cm: duplicate values, no border effects, no spatial cues l Two heating devices on opposite sides, to establish a symmetric gradient l Exact temperature gradient measured in real time by embedded thermocouples l Thermal Insulated Ring-shaped Aluminum Runway l zones per side (specular), 40cm2 ea. 12 l Test results automatically recorded via dedicated camera (included) & ANYmaze video-tracking software l Including a set of 4 dual (visible/I.R.) lights Ugo Basile: more than 25,000 citations

TGR THERMAL GRADIENT RING In recent years the cellular and molecular mechanisms of temperature sensing and thermoregulation are subject of intensive research. Data Collection and Management To overcome limitations evidenced in other tests, we have designed a novel circular thermal gradient assay, for thermal preference phenotyping, based on the paper “Comprehensive thermal Preference Phenotyping in Mice using a Novel Automated Circular Gradient Assay”, published by University Erlangen-Nuernberg (see Bibliography, method paper). l Preference Temperature time course ± SD Rationale of the Test The...