Pain and Inflammation Devices- Plethysmometer: Measures paw edema in rodents with precision, featuring PC connectivity and a graphic display. Optional accessories include various water cell sizes and a mini-printer.
- Analgesy-Meter: Screens analgesic drugs with digital reading capabilities, offering three force ranges and a version for mice.
Motory Coordination and Activity Devices- Grip Strength Meter: Assesses rodent grip strength for motor function studies.
- Activity Cage: Monitors rodent activity levels.
Ventilators and Gas Anesthesia- Mouse Ventilator: Provides precise ventilation for mice during experiments.
- Gas Anaesthesia Systems: Offers controlled anesthesia for rodents with various accessories.
Behavior, Conditioning, and Reward Systems- Beehive Conditioning Cage Manager: Touch-screen controlled system for conditioning experiments.
- Fear Conditioning Systems: Studies fear responses in rodents.
Behavior, Mazes, and Tracking- ANY-maze VideoTracking System: Software for tracking and analyzing animal behavior in mazes.
- Morris Water Maze: Studies spatial learning and memory.
Tissue Baths, Transducers, and Stimulators- Isolated Organ Baths: Available in various configurations for studying isolated tissue responses.
Miscellaneous Devices- ECT Unit: Used for electroconvulsive therapy studies.
- Lesion Making Device: Creates precise lesions in neurological studies.
Blood Pressure and Vital Functions- Blood Pressure Recorder: Non-invasive device for measuring rodent blood pressure.
Metabolism and Feeding Behavior- Basic Metabolic Cages: Studies metabolic rates and feeding behavior in rodents.
Muromachi Microwave Fixation- Muromachi Microwave Brain Fixation System: Rapid brain fixation system for research studies.
Key Features and Specifications- Devices are PC compatible for data acquisition and analysis.
- Optional upgrades and accessories enhance functionality.
Overview: The document details the Analgesy DAQ upgrade kit and related equipment, including specifications, procedures, and references to scientific studies on pain measurement in animal models.
Specifications: The Analgesy-Meter applies force using a cone-shaped pusher, with a pedal switch and a scale in 10g steps. The Hot/Cold Plate NG offers a temperature range from -5°C to 65°C with a touch-screen interface.
Procedures: The Analgesy-Meter measures force on inflamed tissue, while the Hot/Cold Plate NG is used for narcotic analgesic screening and studying cold receptors.
Norms and Standards: Equipment conforms to CE rules for reproducible measurements, with X-PAD software for data management.
Recommendations: Use the auxiliary Hot Plate for habituation to reduce main unit usage. The Thermal Gradient Ring is recommended for comprehensive thermal preference phenotyping in mice.
Key Data: The Analgesy-Meter's force range varies by model, and the Hot/Cold Plate NG's temperature precision is 0.1°C.
Conclusion: Ugo Basile's equipment is reliable and innovative, suitable for pain and inflammation research in animal models.
Thermal Gradient Ring (TGR) System- Specifications: Features a ring-shaped aluminum runway with a thermal gradient controlled by thermocouples.
- Experimental Configuration: Divided into 12 zones with a temperature gradient from 15°C to 40°C.
- Data Collection: Uses ANYmaze software for recording thermal preference behavior.
Plantar Test (Hargreaves Apparatus)- Purpose: Measures acute nociceptive thermal threshold in laboratory animals.
- Main Features: Automatic detection of paw withdrawal, adjustable IR intensity, and modular animal enclosure.
Tail-Flick Unit- Purpose: Rapid screening of analgesic drugs via heat stimulation on the rat tail.
- Main Features: Automatic detection of animal response and data portability.
IR Heat-Flux Radiometer- Purpose: Calibrates IR sources for consistent power flux and nociceptive stimulus intensity.
Calibration and Specifications
Calibration of the I.R. radiation source is detailed in the instruction manuals for the Tail Flick and Plantar Test. The I.R. Heat-Flux Radiometer includes a heat-flux meter and probe.
Dynamic Plantar Aesthesiometer
Assesses touch sensitivity on the plantar surface of rodents, featuring automatic detection of animal response and consistent force application.
Pressure Application Measurement (PAM)
Measures mechanical pain threshold in joint hypersensitivity models in rodents.
Electronic Von Frey (e-VF)
Applies light touch to the rodent foot, assessing hypersensitivity with automatic recording of animal response.
Bibliography
References various studies and papers related to pain and inflammation.
Introduction
Discusses devices and methodologies for assessing pain and hypersensitivity in animals, focusing on the Electronic Von Frey (e-VF) and Von Frey Hairs.
Electronic Von Frey (e-VF)
Offers continuous force application using a single rigid metal tip, with a control unit and DCA software for data monitoring and analysis.
Von Frey Hairs
Nylon monofilaments used to apply reproducible force to the skin, effective in clinical settings.
Orofacial Stimulation Test
Measures hypersensitivity to thermal or mechanical stimulation in the trigeminal area of rats.
Durham Animal Holders
Designed for use with the Plantar Test and Dynamic Plantar Aesthesiometer, allowing consistent application of stimuli.
Conclusion
Provides detailed specifications and ordering information for various tools used in pain and hypersensitivity research.
Overview: Details instruments used in animal research, focusing on devices for measuring pain sensitivity, grip strength, and activity in rodents.
Durham Holders: Designed for use in the Hargreaves test, offering advantages over traditional holders.
Grip Strength Meter: Measures rodent grip strength, assessing effects of drugs and neural damage on muscle strength.
Multiple Activity Cage: Measures general activity levels in rodents using infrared beams.
Rota-Rod NG: Tests motor coordination in rodents with adjustable speed settings and a touch-screen interface.
Conclusion: Outlines specifications, features, and benefits of each device, emphasizing their role in enhancing research accuracy and efficiency.
Introduction
Provides information on the Ugo Basile Rota-Rod and Treadmill systems for testing motor coordination, activity, and grip strength in rodents.
Specifications- Rota-Rod NG: Features adjustable speed, multiple modes, and silent operation.
- Treadmill: Suitable for rats and mice, with adjustable speed and slope.
Experimental Configuration
X-PAD software allows experiment organization and data management.
Data Collection and Management
Data can be viewed on the device's touch-screen and transferred to a PC.
Combo-Packages
Available for users working with both rats and mice.
Physical Specifications- Rota-Rod: Dimensions and weight specified.
- Treadmill: Dimensions and weight specified.
Connections
Devices include USB ports for data exchange and firmware upgrades.
Bibliography
References scientific papers utilizing these devices.
Overview
Details laboratory instruments for studying rodent behavior and physiology, focusing on devices measuring motor activity, exploratory behavior, and respiratory function.
Rotometer for Freely Moving Animals
Quantifies rotational behavior in mice without restraints.
Hole Board for Exploratory Behavior
Studies exploratory behavior using infrared sensors.
Activity Wheels for Rodent Motor Activity
Measures motor activity over extended periods.
Mouse Ventilator
Provides respiratory support with adjustable tidal volume and rate.
Specifications and Ordering Information
Includes detailed specifications and ordering information for each product.
Overview
Details Ugo Basile's ventilators and related equipment for laboratory use with rodents, cats, rabbits, and small birds.
Rodent Ventilator (Model 7025)
Volume-controlled mechanical ventilator for small animals.
Specifications- Rate and stroke volume specified.
- Dimensions and weight specified.
Cat/Rabbit Ventilator (Model 6025)
Designed for cats, rabbits, and similar-sized animals.
Specifications- Rate and stroke volume specified.
- Dimensions and weight specified.
Bronchospasm Transducer (Model 17020)
Performs bronchospasm tests on laboratory animals.
Gas Anesthesia Systems
Modular and cost-effective solution for animal labs.
Key Features- Digital Flowmeter and manifold specified.
Conclusion
Ugo Basile offers a comprehensive range of ventilators and anesthesia systems for laboratory animal research.
Overview
Details Ugo Basile's Gas Anesthesia System for anesthetizing animals of various sizes.
Digital Flowmeter
Features a wide flow range and fine resolution.
Nose-cone/Masks with Diaphragm
Ensures proper positioning and reduces user exposure to anesthetic gases.
Induction Box
Cost-effective solution for confining animals during anesthesia.
Dual Diverter Manifold with Humidifier
Allows anesthetic gas flow to be diverted to two independent devices.
Multiple Delivery System
Connects up to six devices to one anesthesia system.
F/AIR Scavenger
Handles waste anesthetic gases with activated charcoal canisters.
Ordering Information
Includes detailed ordering information for various configurations and accessories.
Rodent Warmer
Maintains animal temperature during surgical procedures.
Beehive System
Modular system for conditioning tests with a touch-screen controller.
Overview: Details the Fear Conditioning (FC) System and related behavioral research equipment.
Fear Conditioning System:- Components: Includes an FC-Unit with various features and an FC-cage for mice or rats.
- Software: ANY-maze software controls experimental parameters and analyzes data.
- New Features (Version 2.1): Simplified setup with USB connectivity and enhanced control.
Startle/PPI System:- Purpose: Studies startle response and prepulse inhibition in animals.
- Components: Includes a controller, software, and isolation cubicle.
- Features: Configures trials with randomizable parameters.
Active Avoidance Set-Up:- Purpose: Enables avoidance experiments with a flexible schedule.
- Components: Includes a programming/recording unit and cages.
- Features: Supports multiple cage setups and includes a scrambling shocker.
Ordering Information: Provides detailed ordering information for various components and systems.
Bibliography: References studies utilizing Ugo Basile equipment.
Overview: Describes the Ugo Basile Passive Avoidance Test instruments for assessing memory function in rodents.
Instrument Description: Includes a controller and a cage divided into two compartments.
Specifications: Features a programming/recording unit with adjustable parameters.
Step-Through and Step-Down Tests: Measures latency as an indicator of memory retention.
Learned Helplessness: Involves exposing rodents to inescapable stress to study depression and memory impairment.
Applications and Research: Cites research papers utilizing the Passive Avoidance Test.
Ordering Information: Provides ordering information for system components.
Conditioned Place Preference Box (CPP)
Evaluates the abuse potential of substances and the motivational effects of drugs.
Main Features:- Interchangeable floors and contexts for tactile and visual stimulation.
- Optimized for video-tracking software.
Ordering Information: Includes floor patterns and wall context kits.
Lickometer - Vogel Test
Assesses anxiolytic effects of drugs using a drinking-conflict paradigm.
Main Features:- Up to 5 animal chambers with adjustable shock intensity.
Ordering Information: Includes components for rat and mouse setups.
Sociability Apparatus (3-Chambered Social Test)
Assesses sociability and interest in social novelty in rodent models.
Main Features:- Works with basic video-tracking software.
Ordering Information: Includes models with opaque or transparent walls.
Agora Maze (Socio-Box Test for Mice)
Assesses social skills in mouse models.
Agora Maze Overview:
Evaluates social interaction, memory, and novelty preference in mice.
Main Features:- Optimized for videotracking with high contrast flooring.
Applications:- Studies on social interaction and psychiatric disorders.
Procedure:
Involves a habituation session followed by a test session.
Atlantis Platforms for Water Maze Experiments:
Provides automated control of platform height for spatial learning assessments.
Main Features:- Hydraulic operation with remote control.
Specifications:- Four independent channels with a vertical range of 25-35 cm.
ANY-maze Software:
Comprehensive video tracking system for automating behavioral tests.
Main Features:- Flexible design for various experimental setups.
Animal Mazes:
Includes water mazes and Barnes mazes optimized for video tracking.
Overview
Details specifications and descriptions of behavioral testing mazes and equipment for rodent research.
Maze Specifications- Elevated Plus-Maze and Zero-Maze: Made from high-tech metal alloy.
Light/Dark Box (Light/Dark Conflict Test)
Measures anxiety-like behavior in mice.
Multi-Maze System
Configurable as a Y-Maze, T-Maze, or 8-Arm Radial Maze.
Forced Swim Test with Water Wheel
Used for screening antidepressants by measuring escape attempts.
Ordering Information
Customizable options available for colors and dimensions.
Specifications:
Water wheel specifications and device connections detailed.
Procedures:
Tank disassembly and data analysis procedures outlined.
Standards and Recommendations:
Device powered via USB with rotation encoder for scoring.
Method Papers:
References studies focusing on behavioral tests for antidepressants.
Ordering Information:
Includes Forced Swim Test and ANYmaze Module.
Isolated Organ Baths:
Designed for recording tissue contraction/release.
Superfusion System:
Designed for neurotransmitter release studies.
Isometric Transducers:
Designed for precise force measurement in muscular preparations.
Overview
Details transducers and data acquisition systems offered by Ugo Basile.
Isotonic Transducer
Designed for investigating isotonic contractions in isolated organs.
DataCapsule-Evo Digital Recorder
Advanced 8-channel data acquisition system with high resolution.
Electroconvulsive Therapy (ECT) Unit
Designed for neurochemical and neuropharmacological research.
Additional Products and Ordering Information
Lists additional products and emphasizes compatibility checks.
Conclusion
Ugo Basile offers high-quality equipment for physiological research.
Overview
Details scientific instruments and devices for neuroscience and biomedical research.
1. ECT Monitor
Accessory for safely connecting an oscilloscope to monitor ECT output.
2. Lesion Making Device
Creates localized lesions in small animals using direct current.
3. Stereotaxic Instruments
Used for precise alignment in stereotaxic procedures.
4. Infusion Pumps by KDS
Micro-processor controlled syringe pumps for high precision metering.
5. Wireless EEG & LFP Recording - NAT Device
Compact, wireless device for biosignal data recording in rodents.
Conclusion
Provides comprehensive technical specifications and operational guidelines for each device.
Specifications and Features
Outlines specifications and features of devices used in animal research.
NAT Device
Designed for wireless recordings in rodents with user-friendly features.
BP Recorder
Used for non-invasive blood pressure measurement in rats and mice.
MouseOx Plus
Non-invasive vital signs monitor for small animals.
Ordering Information
Provides detailed ordering information for each device.
Bibliography
References scientific papers utilizing these devices.
MouseOxPlus System Specifications:
Includes various sensors and physical dimensions.
Metabolic Cages Overview:
Designed for simplicity and interchangeability, complying with regulations.
Metabolic Cage Components:
Includes various components for effective separation of feces and urine.
Innovative Design Features:
Facilitates retrofitting and upgrading to a Feeding Analyser.
Microwave Brain Fixation System:
Halts brain chemical activity rapidly, ensuring safety and reproducibility.
Ordering Information:
Includes models and components for metabolic cages and the microwave fixation system.