BRACHYVISION TREATMENT PLANNING SYSTEM FEATURE SHEET The BrachyVision™ treatment planning system simplifies the development of complex brachytherapy treatment plans. A comprehensive toolset provides the infrastructure for increased consistency and efficiency in your planning process. From the routine to the unusual, BrachyVision allows you to customize your plans to your patient’s individual disease. Adaptive volume optimization (AVOL) allows users to increase efficiency by creating clinical plans in less time.* The optimization methodology attempts to match the specified DVH limits to structures (or lines) while creating smoother dwell times and fewer hot spots. * As compared to manual techniques

COMPREHENSIVE BRACHYTHERAPY PLANNING • Automated segmentation tools © • State-of-the-art drawing and editing tools © • Cut/paste structures from one image set to another © • Draw on any image modality © Source contribution displays the sources that contribute the most to the dose at a given point and updates the dwell times. Image registration • CT, MRI, CBCT, and PET registration support © • Deformable and rigid registration** © • Anatomical match point © • 3D color image blending © • Moving or split window graphical verification © Image acquisition • Acquire images using DICOM 3.0 or directly...

Applicator data entry Standardizing and streamlining workflow • Digitize directly on 3D image • Care Paths - Guides users through their required tasks E • Orthogonal/semi-orthogonal plane films • Reconstruction jig • Coordinate entry • Automatic applicator identification and source placement • Solid applicator library*** - Standardizes treatment protocols and department processes E • Clinical protocols • Plan templates - Standardize the generation and review of any plan Plan evaluation • Side-by-side plan comparison • Multiple planning modality comparison • Plan summation/subtraction - Allow...

SYSTEM WIDE INTEGRATION 3 q Prescribe BRACHYTHERAPY INTEGRATION 1. Patient scheduled in ARIA 2. Treatment plan created in BrachyVision and scheduled in ARIA Unique™ solution 3. Afterloader console pulls treatment plan from ARIA 4. After patient treatment, afterloader console returns the treatment record to ARIA ARIA oncology information system ProBeam™ proton therapy system TrueBeam™ system 5. Afterloader console updates the appointment status 6. RT Summary and Patient Summary display the treatment record and dose in ARIA BrachyVision treatment planning system Varian system database Trilogy®...