Catalog excerpts
Magnetic Microspheres for cfDNA Extraction As one of the core technologies in precision medicine, NGS-based liquid biopsy has been widely used in clinical practice. Efficient extraction and purification of cfDNA is a solid foundation to ensure accurate and reliable test results. However, due to the extremely low concentration of target cfDNA in plasma and the complexity of biological samples, it is difficult to efficiently extract and purify cfDNA. VDO Biotech has specially developed cfDNA extraction magnetic microspheres for plasma samples to help improve the efficiency and accuracy of liquid biopsy. Large specific surface area, strong binding capacity Super paramagnetic microspheres, excellent resuspension performance Special surface modification, strong nucleic acid adsorption capacity and easy elution Fast magnetic response and magnetic absorption, no magnetic residue Large-scale production capacity is up to >100 L/batch, batch-to-batch consistency ensures high reproducibility Workflow of cfDNA extraction using magnetic microspheres Nucleic acid Magnetic microspheres Purified nucleic acid Protein and other impurities
Open the catalog to page 1Case study of cfDNA extraction using magnetic microspheres Sample: 1ml plasma Magnetic Microspheres Company A Sample 1 Sample 2 Sample 3 Sample 1 Sample 2 Sample 3 Magnetic Microspheres Company B Plasma Elution Volume Concentration Sample: 1ml plasma Sample Plasma Elution Volume Concentration Compared with Company A and B, the cfDNA extracted by VDO magnetic microspheres is superior in both yield and purity (using Qubit quantification, Agilent Bioanalyzer 2100 for fragment analysis) Brownish black Surface Group Brownish yellow Other specifications can be customized according to customer...
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