Cystic Fibrosis (CF) StripAssay®
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Cystic Fibrosis (CF) StripAssay® - 1

CF StripAssays® Identify the most relevant CFTR mutations and variants for newborn screening and confirmatory genotyping Cystic Fibrosis (CF) is the most common life-limiting autosomal recessive disorder in the Caucasian population. The disease incidence is estimated to be 1 in 2,500 to 4,000 live births. Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) represents an anion channel which is responsible for the salt-, fluid- and pH-balance in secretory and absorptive epithelial tissues. Mutations in the CFTR gene lead to dysfunction of chloride transport across cell membranes. Affected children commonly experience decreased pulmonary function along with persistent respiratory infections, pancreatic insufficiency and malnutrition. CFTR genotyping enables early diagnosis in newborn screening and minimizes emotional stress for parents. ViennaLab offers reliable and convenient reverse-hybridization assays tailored to population-specific mutations in different regions.

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Cystic Fibrosis (CF) StripAssay® - 2

ESTABLISHED INNOVATIONS IN DIAGNOSTICS ViennaLab CF StripAssays® Simple protocol for complex diagnostic questions • Manual or automated processing • No expensive lab equipment Ready-to-use reagents CE/IVD-labeled kits including DNA extraction The three steps of the StripAssays® Step Order Information: CF StripAssay® 4-410 (10 tests/kit) • CF StripAssay® TUR 4-420 (10 tests/kit) • CF StripAssay® GER 4-430 (10 tests/kit) ViennaLab offers StripAssays® for a wide range of diagnostic applications. Visit www.viennalab.com January 2021 • ISO 13485 Manufacturer: ViennaLab Diagnostics GmbH...

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