Genie® II Flier
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Molecular Diagnostics Made Simple Genie® II is a sophisticated instrument that enables sensitive detection of bacteria and viruses at a molecular level. This powerful and extremely flexible platform allows isothermal amplification of DNA and RNA to take place in a compact and portable device. The instrument is supported by specially-designed tubes and highly efficient reagents to promote ease-of-use and ultra rapid detection capability, offering a complete solution to many nucleic acid detection requirements. Molecular detection of DNA or RNA by isothermal amplification in under 15 minutes Highly sensitive optics for detection of fluorescence and luminescence Two independent heating blocks incorporating precise control up to 99°C Compact, lightweight and fully portable with internal rechargeable battery Operation without a computer via a large touchscreen panel Operates with two specially-designed strips of 8 tubes, which can be used independently or together for a 16 sample run Software is simple to use and yet powerful in its analysis. Convenient ready to use reagents fully optimised for use on Genie® II Low price and cost of ownership OptiGene Limited

Genie® II allows molecular detection to be truly portable, sensitive and fast. The Genie® II allows real-time isothermal amplification to be performed on a low power portable platform. The closed tube system used in Genie® II avoids any post-amplification handling thereby eliminating laboratory contamination from the amplified product. Genie® II contains an internal rechargeable battery, allowing operation for a full day without the requirement The Genie® II system includes two independent heating blocks, each taking an 8-microtube strip optimised for efficient thermal transfer. The...

Molecular Diagnostics Made Simple LAMP Isothermal Amplification Using LAMP, a novel isothermal nucleic acid amplification technology developed by Eiken Chemical Co., Japan, together with the Genie® II instrument, a rapid test was produced for the detection of Shiga toxinproducing E. coli O104 (STEC O104:H4). From the published genome sequence, LAMP primers were designed for two specific targets, stx2 and the O104 antigen gene cluster, using the LAMP Designer software. Following optimisation of the reactions conditions, low copies were detected in <10 minutes using the Genie® II instrument...

Molecular Diagnostics Made Simple Isothermal Mastermix This isothermal amplification mix allows fluorescence detection of the product on the Genie® II platform but may also be used on generic qPCR instrumentation. An anneal curve can then be generated to confirm the product. This eliminates the need for gel electrophoresis or turbidity detection and allows for a closed-tube system. OptiGene Isothermal Mastermixes are fully licensed for LAMP use by Eiken Chemical Company. OptiGene Isothermal Mastermix can be used with RCA, SMAP and many other amplification technologies. Genie® II strips...