OptiGene Leaflet & Catalogue
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COMPANY PROFILE OptiGene Limited was formed in 2008 to develop and deliver advanced molecular diagnostics solutions for applications across a range of market sectors. The goal was to harness the inherent advantages of isothermal amplification of DNA and RNA to enable testing at point-of-application. OptiGene has brought to market a number of innovative products that support sensitive and specific detection of bacteria and viruses for use in the fields of plant health, food safety, veterinary medicine, environmental monitoring and healthcare. These products support rapid detection from crude samples that normally require very simple preparation. An increasing number of OptiGene’s partners and customers are applying isothermal amplification of DNA and RNA to detection of human infectious diseases and bacterial infections. This method has greatest advantage where rapid results are needed and is particularly beneficial in fields such as disease screening, point-of-care diagnostics and pathology. Examples include: detection of antibiotic resistant bacteria inside 15 minutes, screening for MRSA direct from swab in less OptiGene has exploited its expertise in both instrument design and enzymology to develop a sophisticated open platform that will support all isothermal amplification methods. State-of-theart instrumentation is supported by specially-designed plastic strips that have lockable caps and reagents that offer worldleading reaction rates. Ultra-sensitive molecular detection that has been constrained to laboratory use by highly-qualified personnel and taking hours to complete can now be deployed to point-of-application and run with very little training, producing results in single minutes. than 30 minutes and identification of Meningitis in around 10 minutes. Food safety & authenticity WORLDWIDE DISTRIBUTORS Country Company OptiGene has developed LAMP tests for key food pathogens and for use in meat speciation. The tests are run using OptiGene’s ‘Lyse & LAMP’ United States process that is very simple to perform. Virtually any type of sample Beijing Suntrap Science & Technology Co.,Ltd. (including raw meat, cooked meat, cheese and processed products) can be used and the tests complete in around 30 minutes. Speciation South Korea Novazym Polska tests are now available for a large range of animals, many white fish and InterLabService, Moscow for important crops used in processed foods, such as soya. Amplex BioSystems GmbH Amplex BioSystems GmbH Taiwan (ROC) HUI-SHENG International Corporation Insko Tibbi Uretim ve Arastirma San. ve Tic. Ltd. Sti assay development has been ongoing since the beginning of 2013 and Belgium, Luxembourg Vision4Care & Netherlands AmpliGene India Biotech Pvt Ltd PLANT HEALTH OptiGene is fully licensed to manufacture and sell kits for LAMP tests SHORTFORM CATALOGUE that are used to detect plant diseases and pests. Simple sample Product Catalogue No. Quantity preparation, ease of use and fast running time combine to offer distinct Prism mini centrifuge advantage over competing technologies. The Forestry Commission and LAMP Designer software (3 users) Genie tubes small pack size Isothermal master mix (standard) Genie tubes large pack size Isothermal master mix (standard) - no dye Cooling block for setup (Block A) Isothermal master mix (standard) - dried Cooling block for setup (Block B) Isothermal master mix (fast) Cooling block for setup (Blocks A and B) Isothermal master mix (fast) - no dye Robust carry case for Genie II Isothermal master mix (fast) - dried Robust carry case for Genie III others have deployed the Genie system in forests and woods around the UK to detect the presence of the incurable Ash dieback disease (Chalara fraxinea) in order to reduce its spread. VETERINARY DIAGNOSTICS OptiGene’s cooperation with international reference laboratories and University veterinary schools has led to the development of many animal disease tests based on the LAMP isothermal method. The test OptiGene isothermal master mixes are sold for use in LAMP under license from Eiken Chemical Company. Genie is a registered trademark of OptiGene Ltd. targets have included notifiable diseases, zoonotic diseases (that can be transferred to humans) and animal pathogens. Some tests have been specifically developed for identifying disease in farm animals while others are aimed at companion animal diagnostics. OptiGene Limited: Unit 5, Blatchford Road, Horsham, West Sussex RH13 5QR UK T: +44 (0) 1403 274980 F: +44 (0) 1403 271017 E: info@optigene.co.uk I: www.optigene.co.uk MOLECULAR DIAGNOSTICS MADE SIMPLE ISOTHERMAL AMPLIFICATION OF DNA AND RNA

Master mixes Genie II has been the flagship product of OptiGene since its launch early in 2011. It is a compact and portable instrument that supports any isothermal DNA / RNA amplification method. It runs stand-alone without the need for a computer and is operated from a simple user interface from a large touchscreen display. This extremely powerful and flexible platform includes two independent heating blocks, each taking an 8-microtube strip that has been optimised for efficient thermal transfer and sensitive fluorescence measurement. Genie® II has an internal rechargeable battery,...