Warner Instruments The Planar Lipid Bilayer Workstation the only complete tool specifically designed for sophisticated planar lipid bilayer research work 1. a task or duty, 2. to operate or cause to operate effectively station 1. the place from which a service is provided or operations are directed INSTRUMENTS A Harvard Apparatus Company

work 1. a task or duty, 2. to operate or cause to operate effectively station 1. the place from which a service is provided or operations are directed -► designed to have you quickly up and running — • Integrated instrumentation for Planar Lipid Bilayer recording • Simple and integrated design • Complete System •Optional power line conditioning • Popular data acquisition packages •Available on-site setup and training -O- 2 Warner Instruments • Phone (203) 776-0664 • Toll Free U.S. (800) 599-4203 • Fax (203) 776-1278 • www.warneronline.com

system 1. a group of interacting elements functioning as a complex whole, 2. a network, 3. method or procedure component 1. a constituent part, 2. being or functioning as a part of System Components The complete Planar Lipid Bilayer Workstation includes: Vibration isolation table Faraday cage Perfusion system Bilayer clamp amplifier Planar Lipid Bilayer Workstation Instrument rack Integrated controller for stirplate and lamp Low temperature, noise-free halogen lamp Data acquisition system and software BLM Starter Kit (cables, glass, tubing and brushes) Headstage holder Bilayer stirplate Custom...

training 1. to make or become proficient with specialized instruction and practice, 2. focus or aim Optional On-Site Setup and Training Investigators first entering the arena of research using the planar lipid bilayer can be overwhelmed by the wealth of design and application issues surrounding the proper assembly and use of a Bilayer Workstation. While tractable, this state of affairs can result in an investigator choosing a less effective means to achieve his or her research goals. Warner Instruments recognizes the need to make this technology more accessible and is the only company to establish...

The Planar Lipid Bilayer (BLM) Workstation from Warner Instruments integrates every significant component required for the use of a working BLM rig. This unique device allows the user to quickly get up to speed in performing research using this powerful technology. The BLM Workstation is comprised of an FC Series Faraday cage, a BenchMate vibration isolation table from Kinetic Systems, our BC-535 bilayer clamp amplifier and LPF-8 8pole Bessel filter, a SUN-1 halogen lamp, a SPIN-2 bilayer stirplate, the SUNStir integrated controller (for the stirrer and lamp), and the BPS-2 perfusion system....

system 1. a group of interacting elements functioning as a complex whole, 2. a network, 3. method or procedure component 1. a constituent part, 2. being or functioning as a part of Bilayer Clamp Amplifier The BC-535 is the newest version of our popular bilayer clamp amplifier. Warner Instruments is the only company to supply an instrument specifically designed for research using planar lipid bilayer technology and this device forms an integral component of the BLM Workstation. Major improvements in this model include: • Reduced noise and wider bandwidth • Improved stability with gains to 1000...

Measured with 8-pole Bessel filter at specified cutoff frequency Frequency range Open input 100 pF at input DC to 1 kHz 0.060 pA RMS 0.82 pA RMS DC to 100 Hz 0.009 pA RMS 0.28 pA RMS Input commands Internal Hold Command In Junction zero AutoZero or manual adjust. AutoZero lockout feature. Cycle time 1.5 s. Correction to ±120 mV. VCO with off switch and volume control. Internal speaker and external speaker output. Capacitance test Triangle wave applied to command electrode. Derived membrane capacitance read from meter up to 1000 pF. Calibrated (1 mV/pF) square wave available at Im output. Cap...

system 1. a group of interacting elements functioning as a complex whole, 2. a network, 3. method or procedure component 1. a constituent part, 2. being or functioning as a part of FC Series Faraday Cages • Convenient benchtop design • Enclosed vibration isolation table • Passive or active support mechanisms • Large access doors • Magnetic closures • Solid brass grounding block • Durable powder coat finish The Faraday cage provides critical shielding of electromagnetic interference from outside sources and is an integral component of the Bilayer Workstation. FC Series Faraday cages from Warner...

Faraday Cage Specifications Dimensions Aluminum with durable powder coat finish. Solid brass grounding block. Electrically continuous cage with solid wall construction. Cage base accommodates 16” x 19” vibration isolation table (either passive or active support) manufactured by Kinetic Systems, Inc. Table top forms cage floor. Large panel doors with magnetic closures. Dual fan-fold front doors. Large panel doors on top and sides. Cage base has wing doors for access to vibration isolation table controls. Access ports on back panel for electrical connection to cage contents. Specifications are...

system 1. a group of interacting elements functioning as a complex whole, 2. a network, 3. method or procedure component 1. a constituent part, 2. being or functioning as a part of Bilayer Chambers and Cuvettes Since the pioneering work on black lipid membranes by Paul Mueller and co-workers in the early ‘60s, several generations of membrane biologists have exploited this model membrane for biophysical and reconstitution studies. The planar bilayer formed by painting lipids across a small aperture in a partition is one of the simplest techniques available to the novice and expert alike, and the...

Bilayer Chambers and Cuvettes to reduce mechanical noise artifacts. A 2 x 5 mm or 2 x 7 mm Teflon-coated stirbar is supplied with each chamber. Polyethylene centrifuge tubes (supplied) serve as intermediate wells for electrical connections between the headstage electrodes and the cup or chamber. Chambers include a nylon screw and rubber plug to secure the cups during use. The classic model has a window for viewing the aperture during membrane formation. Classic Models BCH-13A and BCH-22A Two classic models are offered: The BCH-13A is a small volume chamber (1.0 ml) with a 13 mm (1/2”) diameter...