FORUM Glaucoma Workplace 2.0 from ZEISS
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FORUM Glaucoma Workplace 2.0 from ZEISS Clinical Interpretation Guide

ZEISS FORUM Glaucoma Workplace 2.0 For years, doctors have asked for the operational capability to analyze data from their Humphrey® Field Analyzer (HFA™) using a Mac or PC. They have also requested greater integration of HFA and CIRRUS™ analysis data in a single report. Based on this feedback, ZEISS developed the FORUM® Glaucoma Workplace. This new workplace application allows doctors to change baselines for Guided Progression Analysis™ (GPA™) and generate HFA reports using a Mac or PC. They can also combine structure and function test data into a single integrated report. ZEISS FORUM...

The diagnosis and management of glaucoma relies on the assessment of visual field test status and progression. The GPA Summary Report can help estimate the current stage of visual loss and rate of progression, to support the assessment of a patient's risk of future vision loss. V. VFI Rate of Progression Analysis Trend analysis of the patient's overall visual field history. 2) VFI Plot Regression analysis of VFI values and 2- to 5-year projection. (5) Glaucoma Hemifield Test (GHT) Provides a plain language classification of 30-2 and 24-2 test results based upon patterns of loss commonly...

Understanding the GPA Summary Electronic Report Dual Baseline Create a dual baseline showing a patient's original baseline and progression. Pioneered by Boel Bengtsson, PhD1 as a more intuitive assessment of visual Baselines, allows the user to compare function, VFI is designed to better rates of progression before and after a reflect the vision associated quality of significant change in therapy, such as life. VFI is center-weighted to better surgery. The initial selection of a SITA™ correspond with the distribution pattern Standard or SITA Fast™ Exam determines of ganglion cells across the...

VFI Bar To the right of the VFI Plot is the VFI Bar. The VFI Bar indicates the patient's current VFI value. In addition, when the results of the regression analysis are displayed, the VFI Bar will also graphically indicate a two- to five-year projection of the linear regression line into the future, shown as a broken line. The length of projection is equal to the number of years of HFA data that is available, up to a maximum projection time of five years. Deviation from Baseline Plot The deviation from Baseline Plot compares the pattern deviation of the most recent Follow-up test to the...

Progression Analysis using Mean Deviation If five or more fields are analyzed in a progression analysis, and all test results to be analyzed were run with the same strategy, ZEISS FORUM Glaucoma Workplace will automatically perform a linear regression analysis of MD, VFI, or both. Baseline Exams Document initial visual field status. Selected Follow-up Visual Field Report of selected follow-up visual field including VFI, MD, PSD, the Progression Analysis Probability Plot and the GPA alert.

Intraocular Pressure (IOP) If IOP values are entered through the HFA or ZEISS FORUM Glaucoma Workplace, the IOP values are displayed in a graphical representation. ZEISS FORUM Glaucoma Workplace will allow the user to compare the graphics for MD, VFI and IOP all in a single report. Complete Access to all standard HFA Analyses ZEISS FORUM Glaucoma Workplace supports all standard HFA Visual Field Analyses.

This is an example of a patient with visual field progression that may be statistically significant but may not be clinically significant. While the event analysis, GPA Alert, indicates "Possible Progression" (3), the measured rate of progression in VFI is only 0.1% per year and the confidence interval on that rate estimate is narrow (2). If the present rate of progression continues, this patient would not seem to be presently at substantial risk of visual disability during his lifetime. 1 Patient was 81 years old at the time of the most recent test. 0 VFI slope is nearly flat and the...

This is an example of a patient with statistically significant and possibly clinically significant progression. This patient's visual field loss is measurably progressing based upon the VFI slope and the GPA alert (3 and 4 below). The patient may be at significant risk of further visual loss in the future. These findings can be weighed in the context of patient life expectancy and also relative to the possible risks associated with any contemplated escalation in treatment. VFI Sample Case 2 [MmtMi Apr 01,1822 Cantor Main Central 24-2 Threshold Test Graytooe Pattern Deviation Graytone...

// INTEGRATION MADE BY ZEISS In addition, optic nerve head parameters Report presents a clinical summary are compared to normative limits. of patient status, as derived from the The Combined Report presents a clinical summary of patient status in a simple and easy-tounderstand format. HFA and the CIRRUS OCT analyses. The report is displayed in a simple, easyto-understand format. It maps the anatomical relationship between visual field test points in the Humphrey 24-2 or 30-2 test pattern and regions of the Retinal Nerve Fiber Layer (RNFL). This mapping was developed based on the work of Dr....

Central 24-2 Threshold Test HFA Visual Field Central 24-2 Threshold Test OS I Gra *_ VFI: 90% GHT is.de Normal Limrts

HFA Test Data Results of the HFA test are shown in three formats: Graytone Plot, Total Deviation and Pattern Deviation Probability Maps. MU Central 24-2 Threshold Test :: p<£% FP & FN - False positive and false negative response rate estimates VFI - Visual Field Index MD - Mean Deviation PSD - Pattern Standard Deviation GHT - Glaucoma Hemifield Test Optic Nerve Head Analysis and RNFL Deviation Map Comparison display of the Retinal Nerve Fiber Layer (RNFL) thickness with normative data. Areas of RNFL that are outside normal limits are shown in yellow (P < 5%) and red (P < 1%). Violet -...

HFA and CIRRUS Combined Structure Function Section The Structure Function Combined Display divides the visual field into six sectors based upon the typical patterns of retinal nerve fibers emanating from the optic nerve. This mapping was based on the publication of Dr. Garway-Heath, et al.4 The OCT display is flipped along the horizontal axis to correspond to the orientation of the Visual Field data. The mean RNFL thickness in each of the six visual field sectors is compared to age-corrected normal values, with yellow indicating deviations from normal that are statistically significant at P...